Impressive progress has been made over the last several years toward understanding how
almost every aspect of the immune system contributes to the expression of systemic …

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem
involvement. It is multifactorial and involves epigenetic, genetic, ecological, and …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of
immune tolerance and sustained production of autoantibodies. Multiple and profound T cell …

Microglia are the primary immune cells of the CNS, carrying out key homeostatic roles and
undergoing context-dependent and temporally regulated changes in response to injury and …

Patients with systemic lupus erythematosus (SLE) experience neuropsychiatric symptoms.
The term neuropsychiatric SLE (NPSLE) is a generic term that refers to a series of …

The neuropsychiatric involvement in systemic lupus erythematosus (NPSLE) is a challenge
for clinicians, both at a diagnostic and therapeutic level. Although in 1999 the American …

Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

Lupus vasculitis (LV) is one of the secondary vasculitides occurring in the setting of systemic
lupus erythematosus (SLE) in approximately 50% of patients. It is most commonly …

Neuropsychiatric lupus (NPSLE) is a frequent manifestation of systemic lupus
erythematosus (SLE) that occurs in 40–90% of SLE patients; however, the underlying …

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease with a
complex pathogenesis. Neuropsychiatric systemic lupus erythematosus (NPSLE) is a …