Proliferation markers, such as proliferating cell nuclear antigen (PCNA), Ki-67, and
thymidine kinase 1 (TK1), have potential as diagnostic tools and as prognostic factors in …

Nucleotide biosynthesis proceeds through a de novo pathway and a salvage route. In the
salvage route, free bases and/or nucleosides are recycled to generate the corresponding …

Studies with molecular and immunological techniques identified and mapped the transcript
encoding glycoprotein D (gD) of equine herpesvirus 1 KyA, as well as two continuous gD …

The aim of this investigation was to synthesize and test a novel metabolically stable
iodinated nucleoside as a proliferation-imaging agent for SPECT. Methods: 5-Iodo-4′-thio …

Gene expression of sterol regulatory element-binding proteins 1a, 1c, and 2 (SREBP-1a,-1c,
and-2) and of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) synthase, HMG-CoA …

Thymidine kinase catalyzes the first step in the nucleotide salvage pathway by transferring a
phosphate group to a thymidine molecule. In mammals thymidine kinase supplies …

Fialuridine (FIAU) is a thymidine analog effective against hepatitis B virus. Toxicity
associated with FIAU treatment included clinical signs consistent with mitochondrial …

Beginning with the pioneering work of Salic and Mitchison (2008), the application of
thymidine analogue 5-ethynyl-2′-deoxyuridine (EdU) for the detection of cells replicating …

Начиная с пионерской работы Salic и Mitchison (2008), активно расширяется
применение аналога тимидина 5-этинил-2-дезоксиуридина (EdU) для выявления …

Thymidine kinase 1 (TK1) phosphorylates thymidine nucleosides to generate thymidine
monophosphate. This reaction belongs to the pyrimidine salvage route that is …