Epidemiology of human African trypanosomiasis

JR Franco, PP Simarro, A Diarra… - Clinical epidemiology, 2014 - Taylor & Francis
Human African trypanosomiasis (HAT), or sleeping sickness, is caused by Trypanosoma
brucei gambiense, which is a chronic form of the disease present in western and central …

Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment

TK Mackey, BA Liang, R Cuomo, R Hafen… - Clinical microbiology …, 2014 - Am Soc Microbiol
In global health, critical challenges have arisen from infectious diseases, including the
emergence and reemergence of old and new infectious diseases. Emergence and …

Oral fexinidazole for late-stage African Trypanosoma brucei gambiense trypanosomiasis: a pivotal multicentre, randomised, non-inferiority trial

VKBK Mesu, WM Kalonji, C Bardonneau, OV Mordt… - The Lancet, 2018 - thelancet.com
Background Few therapeutic options are available to treat the late-stage of human African
trypanosomiasis, a neglected tropical disease, caused by Trypanosoma brucei gambiense …

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

P Capewell, C Cren-Travaillé, F Marchesi, P Johnston… - Elife, 2016 - elifesciences.org
The role of mammalian skin in harbouring and transmitting arthropod-borne protozoan
parasites has been overlooked for decades as these pathogens have been regarded …

The Atlas of human African trypanosomiasis: a contribution to global mapping of neglected tropical diseases

PP Simarro, G Cecchi, M Paone, JR Franco… - International journal of …, 2010 - Springer
Abstract Background Following World Health Assembly resolutions 50.36 in 1997 and 56.7
in 2003, the World Health Organization (WHO) committed itself to supporting human African …

The human African trypanosomiasis control and surveillance programme of the World Health Organization 2000–2009: the way forward

PP Simarro, A Diarra, JA Ruiz Postigo… - PLoS neglected …, 2011 - journals.plos.org
Background One century ago human African trypanosomiasis (HAT), also known as
sleeping sickness, was believed to curb the development of colonial territories. As soon as …

[HTML][HTML] An update on African trypanocide pharmaceutics and resistance

KI Kasozi, ET MacLeod, I Ntulume… - Frontiers in Veterinary …, 2022 - frontiersin.org
African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

Options for field diagnosis of human African trypanosomiasis

F Chappuis, L Loutan, P Simarro, V Lejon… - Clinical microbiology …, 2005 - Am Soc Microbiol
Human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense or T. b.
rhodesiense remains highly prevalent in several rural areas of sub-Saharan Africa and is …

[PDF][PDF] Human trypanosomiasis caused by Trypanosoma evansi in India: the first case report

PP Joshi, VR Shegokar, RM Powar… - American Journal of …, 2005 - academia.edu
We report an Indian farmer who had fluctuating trypanosome parasitemia associated with
febrile episodes for five months. Morphologic examination of the parasites indicated the …

Do cryptic reservoirs threaten gambiense-sleeping sickness elimination?

P Büscher, JM Bart, M Boelaert, B Bucheton… - Trends in …, 2018 - cell.com
Trypanosoma brucei gambiense causes human African trypanosomiasis (HAT). Between
1990 and 2015, almost 440000 cases were reported. Large-scale screening of populations …