Tolerance to trypanosomatids: a threat, or a key for disease elimination?

D Berthier, SF Brenière, R Bras-Gonçalves… - Trends in …, 2016 - cell.com
So far, research on trypanosomatid infections has been driven by 'disease by
disease'approaches, leading to different concepts and control strategies. It is, however …

[HTML][HTML] Accuracy of Individual Rapid Tests for Serodiagnosis of Gambiense Sleeping Sickness in West Africa

V Jamonneau, O Camara, H Ilboudo… - PLoS neglected …, 2015 - journals.plos.org
Background Individual rapid tests for serodiagnosis (RDT) of human African
trypanosomiasis (HAT) are particularly suited for passive screening and surveillance …

[HTML][HTML] Innovative partnerships for the elimination of human African trypanosomiasis and the development of fexinidazole

P Neau, H Hänel, V Lameyre, N Strub-Wourgaft… - Tropical Medicine and …, 2020 - mdpi.com
Human African Trypanosomiasis (HAT or sleeping sickness) is a life-threatening neglected
tropical disease that is endemic in 36 sub-Saharan African countries. Until recently …

[HTML][HTML] Screening North American plant extracts in vitro against Trypanosoma brucei for discovery of new antitrypanosomal drug leads

S Jain, M Jacob, L Walker, B Tekwani - BMC complementary and …, 2016 - Springer
Abstract Background Human African Trypanosomiasis (HAT) is a protozoan parasitic
disease caused by Trypanosoma brucei. The disease is endemic in regions of sub-Saharan …

[HTML][HTML] Suramin inhibits chikungunya virus replication by interacting with virions and blocking the early steps of infection

IC Albulescu, L White-Scholten, A Tas, TE Hoornweg… - Viruses, 2020 - mdpi.com
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that can cause a
debilitating disease that is primarily characterized by persistent joint pain. CHIKV has been …

Update of transmission modelling and projections of gambiense human African trypanosomiasis in the Mandoul focus, Chad

KS Rock, CI Huang, RE Crump, PR Bessell… - Infectious Diseases of …, 2022 - mednexus.org
Background: In recent years, a programme of vector control, screening and treatment of
gambiense human African trypanosomiasis (gHAT) infections led to a rapid decline in cases …

[HTML][HTML] Human African Trypanosomiasis (sleeping sickness): Current knowledge and future challenges

R Papagni, R Novara, ML Minardi… - Frontiers in Tropical …, 2023 - frontiersin.org
According to both definitions of US Centers for Disease Control and Prevention and World
Health Organization, Neglected Tropical Diseases (NTDs) are a group of preventable and …

Parasitic central nervous system infections in immunocompromised hosts: malaria, microsporidiosis, leishmaniasis, and African trypanosomiasis

DR Snydman, M Walker, JG Kublin… - Clinical infectious …, 2006 - academic.oup.com
Immunosuppression associated with HIV infection or following transplantation increases
susceptibility to central nervous system (CNS) infections. Because of increasing …

[HTML][HTML] The socio-economic burden of human African trypanosomiasis and the coping strategies of households in the South Western Kenya foci

SA Bukachi, S Wandibba… - PLoS neglected tropical …, 2017 - journals.plos.org
Introduction Human African Trypanosomiasis (HAT), a disease caused by protozoan
parasites transmitted by tsetse flies, is an important neglected tropical disease endemic in …

[HTML][HTML] A single test approach for accurate and sensitive detection and taxonomic characterization of trypanosomes by comprehensive analysis of internal transcribed …

AK Gaithuma, J Yamagishi, A Martinelli… - PLoS neglected …, 2019 - journals.plos.org
To improve our knowledge on the epidemiological status of African trypanosomiasis, better
tools are required to monitor Trypanosome genotypes circulating in both mammalian hosts …