Introduction Human African Trypanosomiasis (HAT), a disease caused by protozoan
parasites transmitted by tsetse flies, is an important neglected tropical disease endemic in …

A resurgence of sleeping sickness developed in southern Sudan during the past decade.
Prevalence of confirmed Trypanosoma brucei gambiense infection in humans now exceeds …

Immunosuppression associated with HIV infection or following transplantation increases
susceptibility to central nervous system (CNS) infections. Because of increasing …

Introduction Invasion of the central nervous system (CNS) is the most serious consequence
of Trypanosoma brucei infection, which causes sleeping sickness. Recent experimental data …

New drugs against Trypanosoma brucei, the causative agent of Human African
Trypanosomiasis, are urgently needed to replace the highly toxic and largely ineffective …

To improve our knowledge on the epidemiological status of African trypanosomiasis, better
tools are required to monitor Trypanosome genotypes circulating in both mammalian hosts …

Resin glycosides are secondary metabolites exclusive to the convolvulaceous plants. In this
study, crypthophilic acids A–C (1–3), the first resin glycosides occurring in another family …

Foodborne parasites are a source of human parasitic infection. Zoonotic infections of
humans arise from a variety of domestic and wild animals, including sheep, goats, cattle …

The control and eventual elimination of human African trypanosomiasis (HAT) requires the
expansion of current control and surveillance activities. A systematic review of the published …

Background The polymerase chain reaction (PCR) has been proposed for diagnosis,
staging and post-treatment follow-up of sleeping sickness but no large-scale clinical …