Automatic lung segmentation in routine imaging is primarily a data diversity problem, not a methodology problem

J Hofmanninger, F Prayer, J Pan, S Röhrich… - European Radiology …, 2020 - Springer
Background Automated segmentation of anatomical structures is a crucial step in image
analysis. For lung segmentation in computed tomography, a variety of approaches exists …

Quantification of neonatal lung parenchymal density via ultrashort echo time MRI with comparison to CT

NS Higano, RJ Fleck, DR Spielberg… - Journal of Magnetic …, 2017 - Wiley Online Library
Purpose To demonstrate that ultrashort echo time (UTE) magnetic resonance imaging (MRI)
can achieve computed tomography (CT)‐like quantification of lung parenchyma in free …

Pediatric 129Xe Gas‐Transfer MRI—Feasibility and Applicability

MM Willmering, LL Walkup… - Journal of Magnetic …, 2022 - Wiley Online Library
Background 129Xe gas‐transfer MRI provides regional measures of pulmonary gas
exchange in adults and separates xenon in interstitial lung tissue/plasma (barrier) from …

Advancements in imaging in ChILD

DR Spielberg, J Weinman… - Pediatric Pulmonology, 2023 - Wiley Online Library
Interstitial and diffuse lung diseases in children constitute a range of congenital and
acquired disorders. These disorders present with signs and symptoms of respiratory disease …

Quantitative CT and pulmonary function in children with post-infectious bronchiolitis obliterans

J Kim, MJ Kim, IS Sol, MH Sohn, H Yoon, HJ Shin… - PloS one, 2019 - journals.plos.org
Objective To investigate the feasibility of CT-based quantitative airway and air-trapping
measurements and to assess their correlation with pulmonary function in children with post …

Assessment of pulmonary structure–function relationships in young children and adolescents with cystic fibrosis by multivolume proton‐MRI and CT

F Pennati, DJ Roach, JP Clancy… - Journal of Magnetic …, 2018 - Wiley Online Library
Background Lung disease is the most frequent cause of morbidity and mortality in patients
with cystic fibrosis (CF), and there is a shortage of sensitive biomarkers able to regionally …

Ground‐glass burden as a biomarker in neuroendocrine cell hyperplasia of infancy

DR Spielberg, AS Brody, ML Baker… - Pediatric …, 2019 - Wiley Online Library
Background Neuroendocrine cell hyperplasia of infancy (NEHI) is a rare pediatric interstitial
lung disease (ILD). Distinct chest computed tomography (CT) define its radiographic …

Computed tomography based measurements to evaluate lung density and lung growth after congenital diaphragmatic hernia

T Stoll-Dannenhauer, G Schwab, K Zahn, T Schaible… - Scientific reports, 2021 - nature.com
Emphysema-like-change of lung is one aspect of lung morbidity in children after congenital
diaphragmatic hernia (CDH). This study aims to evaluate if the extent of reduced lung …

Quantitative CT scans of lung parenchymal pathology in premature infants ages 0–6 years

DR Spielberg, LL Walkup, JM Stein… - Pediatric …, 2018 - Wiley Online Library
Background Bronchopulmonary dysplasia (BPD) is a common, heterogeneous disease in
premature infants. We hypothesized that quantitative CT techniques could assess lung …

Lung clearance index and quantitative computed tomography of post-infectious bronchiolitis obliterans in infants

YH Kim, HJ Shin, IS Sol, SY Kim, JD Kim, H Yoon… - Scientific reports, 2017 - nature.com
Post-infectious bronchiolitis obliterans (BO) could be diagnosed via spirometry and chest
computed tomography (CT); however, these tests are limited in infants. We aimed to …