The clinical diagnosis of Parkinson's disease rests on the identification of the characteristics
related to dopamine deficiency that are a consequence of degeneration of the substantia …

Impaired sleep and alertness, initially recognized by James Parkinson in his famous
monograph “An Essay on the Shaking Palsy” in 1817, is one of the most common and …

Many patients with assumed idiopathic REM sleep behavior disorder (RBD) may actually
represent an early clinical manifestation of an evolving neurodegenerative disorder, such as …

Background We postulated that idiopathic rapid-eye-movement (REM) sleep behaviour
disorder (IRBD) represents the prodromal phase of a Lewy body disorder and that, with …

A comprehensive proposal for a conceptual framework for describing conscious experience
in dreams, integrating philosophy of mind, sleep and dream research, and interdisciplinary …

Summary Rapid-eye-movement (REM) sleep behaviour disorder (RBD) is characterised by
loss of muscular atonia and prominent motor behaviours during REM sleep. RBD can cause …

REM sleep behavior disorder (RBD) is characterized by vigorous movements associated
with unpleasant dreams and increased electromyographic activity during REM sleep …

OBJECTIVES: There are limited screening instruments for diagnosis of REM sleep behavior
disorder (RBD) and none for quantifying the severity of disease. We aimed to validate a 13 …

During rapid eye movement (REM) sleep, skeletal muscles are almost paralyzed. However,
in REM sleep behavior disorder (RBD), which is a rare neurological condition, muscle atonia …

Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease. Traditionally, attention has focused on the motor symptomatology of …