Considerations for the use of phage therapy in clinical practice

GA Suh, TP Lodise, PD Tamma… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …

The oral microbiota: community composition, influencing factors, pathogenesis, and interventions

X Li, Y Liu, X Yang, C Li, Z Song - Frontiers in microbiology, 2022 - frontiersin.org
The human oral cavity provides a habitat for oral microbial communities. The complexity of
its anatomical structure, its connectivity to the outside, and its moist environment contribute …

Bacterial defences: mechanisms, evolution and antimicrobial resistance

WPJ Smith, BR Wucher, CD Nadell… - Nature Reviews …, 2023 - nature.com
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …

[HTML][HTML] Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical …

E Peterson, P Kaur - Frontiers in microbiology, 2018 - frontiersin.org
Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

Antibiotic resistance genes from livestock waste: occurrence, dissemination, and treatment

Y He, Q Yuan, J Mathieu, L Stadler, N Senehi, R Sun… - NPJ Clean …, 2020 - nature.com
Antibiotics are widely used in animal husbandry, and various types of antibiotic resistance
genes (ARGs) are frequently detected in livestock waste around the world. Conventional …

[HTML][HTML] Advantages and limitations of bacteriophages for the treatment of bacterial infections

N Principi, E Silvestri, S Esposito - Frontiers in pharmacology, 2019 - frontiersin.org
Bacteriophages (BPs) are viruses that can infect and kill bacteria without any negative effect
on human or animal cells. For this reason, it is supposed that they can be used, alone or in …

Lessons learned from the first 10 consecutive cases of intravenous bacteriophage therapy to treat multidrug-resistant bacterial infections at a single center in the …

S Aslam, E Lampley, D Wooten, M Karris… - Open forum …, 2020 - academic.oup.com
Background Due to increasing multidrug-resistant (MDR) infections, there is an interest in
assessing the use of bacteriophage therapy (BT) as an antibiotic alternative. After the first …

Considerations and caveats in combating ESKAPE pathogens against nosocomial infections

YX Ma, CY Wang, YY Li, J Li, QQ Wan… - Advanced …, 2020 - Wiley Online Library
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

The spread of antibiotic resistance genes in vivo model

S Tao, H Chen, N Li, T Wang… - Canadian Journal of …, 2022 - Wiley Online Library
Infections caused by antibiotic‐resistant bacteria are a major public health threat. The
emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical …

[HTML][HTML] New insights into intestinal phages

R Sausset, MA Petit, V Gaboriau-Routhiau… - Mucosal …, 2020 - Elsevier
The intestinal microbiota plays important roles in human health. This last decade, the viral
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …