Over the last two decades, a multitude of gain-of-function studies have been conducted on
genes that encode antioxidative enzymes, including one of the key enzymes, manganese …

Apoptosis, or programmed cell death, maintains tissue homeostasis by eliminating damaged
or unnecessary cells. However, cells can evade this process, contributing to conditions such …

Molecular pathways involved in cerebral stroke are diverse. The major pathophysiological
events that are observed in stroke comprises of excitotoxicity, oxidative stress, mitochondrial …

Simple Summary Neurodegenerative diseases are characterized by the progressive
degeneration of nerve cells. Some neurodegenerative diseases such as Alzheimer's and …

Neurodegenerative diseases are characterized by degeneration or cellular atrophy within
specific structures of the brain. Neurons are the major target of neurodegeneration. Neurons …

Context: Alzheimer's disease (AD) is a debilitating neurodegenerative condition primarily
afflicting the elderly, causing a progressive decline in cognitive function. It is marked by the …

Background Alzheimer's disease (AD) stands as one of the prevalent irreversible
neurodegenerative conditions marked by gradual cognitive deterioration and neuronal loss …

La perdita di proteostasi è ben documentata durante l'invecchiamento e dipende dal
progressivo declino patologico dell'attività di due principali meccanismi degradativi: il …

Background: Porphyromonas gingivalis, a keystone pathogen implicated in periodontal
disease, has been associated with neurological disorders, such as Alzheimer's disease …

Context: Alzheimer's disease (AD) is a debilitating neurodegenerative condition primarily
afflicting the elderly, causing a progressive decline in cognitive function. It is marked by the …