Visual processing in the fly, from photoreceptors to behavior
Originally a genetic model organism, the experimental use of Drosophila melanogaster has
grown to include quantitative behavioral analyses, sophisticated perturbations of neuronal …
grown to include quantitative behavioral analyses, sophisticated perturbations of neuronal …
Visual circuits for direction selectivity
Images projected onto the retina of an animal eye are rarely still. Instead, they usually
contain motion signals originating either from moving objects or from retinal slip caused by …
contain motion signals originating either from moving objects or from retinal slip caused by …
[HTML][HTML] A single-cell transcriptome atlas of the aging Drosophila brain
K Davie, J Janssens, D Koldere, M De Waegeneer… - Cell, 2018 - cell.com
The diversity of cell types and regulatory states in the brain, and how these change during
aging, remains largely unknown. We present a single-cell transcriptome atlas of the entire …
aging, remains largely unknown. We present a single-cell transcriptome atlas of the entire …
Neuronal diversity and convergence in a visual system developmental atlas
Deciphering how neuronal diversity is established and maintained requires a detailed
knowledge of neuronal gene expression throughout development. In contrast to mammalian …
knowledge of neuronal gene expression throughout development. In contrast to mammalian …
Optimized tools for multicolor stochastic labeling reveal diverse stereotyped cell arrangements in the fly visual system
A Nern, BD Pfeiffer, GM Rubin - Proceedings of the …, 2015 - National Acad Sciences
We describe the development and application of methods for high-throughput
neuroanatomy in Drosophila using light microscopy. These tools enable efficient multicolor …
neuroanatomy in Drosophila using light microscopy. These tools enable efficient multicolor …
[HTML][HTML] Super-resolution mapping of neuronal circuitry with an index-optimized clearing agent
MT Ke, Y Nakai, S Fujimoto, R Takayama, S Yoshida… - Cell reports, 2016 - cell.com
Super-resolution imaging deep inside tissues has been challenging, as it is extremely
sensitive to light scattering and spherical aberrations. Here, we report an optimized optical …
sensitive to light scattering and spherical aberrations. Here, we report an optimized optical …
A complete temporal transcription factor series in the fly visual system
The brain consists of thousands of neuronal types that are generated by stem cells
producing different neuronal types as they age. In Drosophila, this temporal patterning is …
producing different neuronal types as they age. In Drosophila, this temporal patterning is …
[HTML][HTML] The comprehensive connectome of a neural substrate for 'ON' motion detection in Drosophila
Analysing computations in neural circuits often uses simplified models because the actual
neuronal implementation is not known. For example, a problem in vision, how the eye …
neuronal implementation is not known. For example, a problem in vision, how the eye …
Processing properties of ON and OFF pathways for Drosophila motion detection
The algorithms and neural circuits that process spatio-temporal changes in luminance to
extract visual motion cues have been the focus of intense research. An influential model, the …
extract visual motion cues have been the focus of intense research. An influential model, the …
Temporal patterning of Drosophila medulla neuroblasts controls neural fates
In the Drosophila optic lobes, the medulla processes visual information coming from inner
photoreceptors R7 and R8 and from lamina neurons. It contains approximately 40,000 …
photoreceptors R7 and R8 and from lamina neurons. It contains approximately 40,000 …