In people with Parkinson's disease, neuropsychiatric signs and symptoms are common
throughout the disease course. These symptoms can be disabling and as clinically relevant …

Depression, with an estimated prevalence of about 40% is a most common neuropsychiatric
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …

Abstract Background Differentiating early-stage Parkinson's disease (PD) from essential
tremor (ET) is challenging since they have some overlapping clinical features. Since early …

Objective Cerebral small vessel disease (SVD) is associated with motor impairments and
parkinsonian signs cross‐sectionally, however, there are little longitudinal data on whether …

Background Although previously thought to be asymptomatic, recent studies have
suggested that magnetic resonance imaging–visible perivascular spaces (PVS) in the basal …

Parkinson's disease (PD) is a progressive neurodegenerative disease with a global burden
that affects more often in the elderly. The basal ganglia (BG) is believed to account for …

Background The trialed treatment landscape of Parkinson's disease (PD) is extensive, but
up to now, there is no disease-modifying therapy. As the pathophysiology of PD becomes …

There are many documented sex differences in the clinical course, symptom expression
profile, and treatment response of Parkinson's disease, creating additional challenges for …

The relationship between cerebrovascular disease and parkinsonism is commonly seen in
everyday clinical practice but remains ill-defined and under-recognised with little guidance …

Objectives High visit‐to‐visit blood pressure variability (BPV) was found to be associated
with cognitive decline in the elderly. This study aimed to investigate the impact of visit‐to …