Synthetic progestins are used by millions of women as contraceptives and in hormone
replacement therapy (HRT), although their molecular mechanisms of action are not well …

The use of polymers to provide controlled long-term delivery of drugs and other chemicals is
a rapidly emerging field. This review focuses primarily on the applications of these polymeric …

Three women were each given 30 μg levonorgestrel in succession by the intravenous and
oral routes. Another six women were given 150 μg levonorgestrel in the form of a …

Norethisterone, levonorgestrel, cyproterone acetate and gestodene have been used for a
long time in oral contraception and other indications, or are in the process of development …

5 mg lynestrenol-14 C (Lyn), 2.0 mg cyproterone acetate-14 C (CPA) and 0.25 mg d-
norgestrel-3 H (d-Ng), each together with 50μg ethinyloestradiol, were each administered …

Sixty-three women had NORPLANT® implants inserted during the first eight days of the
menstrual cycle. Blood specimens were withdrawn at the time of insertion and every three …

Three voluntary women started a microdose, combined oral contraception (30 μg of EE 2
and 150 μg of d-Ng) within ten hours after an induced abortion on week 8–10 of gestation …

The large number of oestrogen-progestogen formulations available for contraceptive use
was markedly reduced in the late 1960s when many progestogens were withdrawn on …

In long-term studies chlormadinone acetate (CMA) and cyproterone acetate (CPA) have
much more pronounced mammotropic effects in dogs than norethisterone acetate (NA) or …

This report describes the pharmacokinetics of levonorgestrel, gestodene, norethisterone and
cyproterone acetate following subcutaneous administration of oily solutions in the rat …