B cells occupy a vital role in the functioning of the immune system, working in tandem with T
cells to either suppress or promote tumor growth within the tumor microenvironment (TME) …

Personalized medicine tailors therapies, disease prevention, and health maintenance to the
individual, with pharmacogenomics serving as a key tool to improve outcomes and prevent …

The blood proteome holds great promise for precision medicine but poses substantial
challenges due to the low abundance of most plasma proteins and the vast dynamic range …

Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a
potential curative approach for PC, but most patients are unsuitable for operations when at …

Organ-specific metastasis is the primary cause of cancer patient death. The distant
metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of …

Cancer is one of the major public health issues in the world. It has become the second
leading cause of death, with approximately 75% of cancer deaths transpiring in low-or …

A liquid biopsy combined with an exosome-chip (EC) is an important detection tool for early
cancer diagnosis. Exosomes have a crucial function in the exchange of information between …

In the last years, liquid biopsy gained increasing clinical relevance for detecting and
monitoring several cancer types, being minimally invasive, highly informative and replicable …

Immune checkpoint inhibitors (ICIs) have dramatically enhanced the treatment outcomes for
diverse malignancies. Yet, only 15–60% of patients respond significantly. Therefore …

Basic and clinical cancer research requires tumor models that consistently recapitulate the
characteristics of prima tumors. As ex vivo 3D cultures of patient tumor cells, patient‐derived …