Membranous nephropathy: new pathogenic mechanisms and their clinical implications
E Hoxha, L Reinhard, RAK Stahl - Nature Reviews Nephrology, 2022 - nature.com
Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …
Primary membranous nephropathy
WG Couser - Clinical Journal of the American Society of …, 2017 - journals.lww.com
Membranous nephropathy (MN) is a unique glomerular lesion that is the most common
cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are …
cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are …
Rituximab or cyclosporine in the treatment of membranous nephropathy
FC Fervenza, GB Appel, SJ Barbour… - … England Journal of …, 2019 - Mass Medical Soc
Background B-cell anomalies play a role in the pathogenesis of membranous nephropathy.
B-cell depletion with rituximab may therefore be noninferior to treatment with cyclosporine …
B-cell depletion with rituximab may therefore be noninferior to treatment with cyclosporine …
Rituximab or cyclophosphamide in the treatment of membranous nephropathy: the RI-CYCLO randomized trial
Background A cyclic corticosteroid-cyclophosphamide regimen is the first-line therapy for
membranous nephropathy. Compared with this regimen, rituximab therapy might have a …
membranous nephropathy. Compared with this regimen, rituximab therapy might have a …
A proposal for a serology-based approach to membranous nephropathy
AS De Vriese, RJ Glassock, KA Nath… - Journal of the …, 2017 - journals.lww.com
Primary membranous nephropathy (MN) is an autoimmune disease mainly caused by
autoantibodies against the recently discovered podocyte antigens: the M-type …
autoantibodies against the recently discovered podocyte antigens: the M-type …
Pathophysiological advances in membranous nephropathy: time for a shift in patient's care
P Ronco, H Debiec - The Lancet, 2015 - thelancet.com
Membranous nephropathy is a major cause of nephrotic syndrome of non-diabetic origin in
adults. It is the second or third leading cause of end-stage renal disease in patients with …
adults. It is the second or third leading cause of end-stage renal disease in patients with …
Membranous nephropathy
P Ronco, L Beck, H Debiec, FC Fervenza… - Nature reviews Disease …, 2021 - nature.com
Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …
Anti-phospholipase A2 receptor antibody titer predicts post-rituximab outcome of membranous nephropathy
P Ruggenenti, H Debiec, B Ruggiero… - Journal of the …, 2015 - journals.lww.com
Rituximab induces nephrotic syndrome (NS) remission in two-thirds of patients with primary
membranous nephropathy (MN), even after other treatments have failed. To assess the …
membranous nephropathy (MN), even after other treatments have failed. To assess the …
Primary glomerulonephritides
J Floege, K Amann - The Lancet, 2016 - thelancet.com
Most glomerulonephritides, even the more common types, are rare diseases. They are
nevertheless important since they frequently affect young people, often cannot be cured, and …
nevertheless important since they frequently affect young people, often cannot be cured, and …
[HTML][HTML] Membranous nephropathy: integrating basic science into improved clinical management
DC Cattran, PE Brenchley - Kidney international, 2017 - Elsevier
Idiopathic membranous nephropathy (INM) remains a common cause of the nephrotic
syndrome in adults. The autoimmune nature of IMN was clearly delineated in 2009 with the …
syndrome in adults. The autoimmune nature of IMN was clearly delineated in 2009 with the …