[HTML][HTML] The crucial role and mechanism of insulin resistance in metabolic disease

X Zhao, X An, C Yang, W Sun, H Ji… - Frontiers in endocrinology, 2023 - frontiersin.org
Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

Molecular mechanisms by which GLP-1 RA and DPP-4i induce insulin sensitivity

H Yaribeygi, T Sathyapalan, A Sahebkar - Life sciences, 2019 - Elsevier
Glucagon-like peptide-1 is a peptide of incretin family which is used in the management of
diabetes as glucagon-like peptide-1 receptor agonist (GLP-1RA). Dipeptidyl peptidase-4 …

Genome-wide association study of diabetic kidney disease highlights biology involved in glomerular basement membrane collagen

RM Salem, JN Todd, N Sandholm… - Journal of the …, 2019 - journals.lww.com
Background Although diabetic kidney disease demonstrates both familial clustering and
single nucleotide polymorphism heritability, the specific genetic factors influencing risk …

Selective insulin resistance in the kidney

S Horita, M Nakamura, M Suzuki… - BioMed Research …, 2016 - Wiley Online Library
Insulin resistance has been characterized as attenuation of insulin sensitivity at target
organs and tissues, such as muscle and fat tissues and the liver. The insulin signaling …

[HTML][HTML] Insulin resistance in type 1 diabetes mellitus and its association with patient's micro-and macrovascular complications, sex hormones, and other clinical data

D Šimonienė, A Platūkiene, E Prakapienė… - Diabetes Therapy, 2020 - Springer
Introduction The main objective of this research was to evaluate the association of insulin
resistance (IR) with micro-and macrovascular complications, sex hormones, and other …

[HTML][HTML] Serum levels of copper and zinc in diabetic retinopathy: Potential new therapeutic targets

AM Dascalu, A Anghelache… - Experimental and …, 2022 - spandidos-publications.com
Diabetic retinopathy (DR) is a microvascular disorder occurring due to the long-term effects
of diabetes, leading to vision-threatening damage to the retina. The human body has an …

Insulin resistance and risk of vascular events, interventions and mortality in type 1 diabetes

MAG Helmink, M de Vries, FLJ Visseren… - European journal of …, 2021 - academic.oup.com
Objective To identify determinants associated with insulin resistance and to assess the
association between insulin resistance and cardiovascular events, vascular interventions …

Urinary C‐peptide/creatinine ratio: a useful biomarker of insulin resistance and refined classification of type 2 diabetes mellitus

Y Wang, X Zou, X Cai, W Liu, L Chen… - Journal of …, 2021 - Wiley Online Library
Background The urinary C‐peptide/creatinine ratio (UCPCR) is low in patients with type 1
diabetes mellitus, but it has not been well characterized in patients with type 2 diabetes …

[HTML][HTML] Redefining distal symmetrical polyneuropathy features in type 1 diabetes: a systematic review

E Galosi, X Hu, N Michael, JR Nyengaard, A Truini… - Acta Diabetologica, 2022 - Springer
Diabetic neuropathy is among the most frequent complications of both type 1 (T1DM) and
type 2 diabetes (T2DM) and commonly manifests as a distal symmetrical polyneuropathy …

Relationship between estimated glucose disposal rate and type 2 diabetic retinopathy

C Meng, Y Xing, L Huo, H Ma - Diabetes, Metabolic Syndrome and …, 2023 - Taylor & Francis
Purpose To investigate the association between diabetic retinopathy (DR), DR intensity, and
estimated glucose disposal rate (eGDR) in individuals with type 2 diabetes mellitus (T2DM) …