Currently, and globally, we are facing the worst epidemic of psychoactive drug abuse
resulting in the loss of hundreds of thousands of lives annually. Besides alcohol and opioid …

Thymine DNA glycosylase (TDG) is a multifunctional protein that plays important roles in
DNA repair, DNA demethylation, and transcriptional regulation. These diverse functions …

The image on the cover and title page is a stylized dendrogram of paraphyly (see Plate 1.1).
This is, in macroevolutionary terms, an ancestral taxon of two (or more) species or of …

We identified the BCL11A protein in a proximity-dependent biotinylation screen performed
with the DNA glycosylase NTHL1. In vitro, DNA repair assays demonstrate that both BCL11A …

Myostatin (MSTN) is a negative regulator of skeletal muscle development and plays an
important role in muscle development. Fluctuations in gene expression influenced by DNA …

DNA methylation plays an essential role in regulating plant development. Here, we
described an early flowering trifoliate orange (precocious trifoliate orange, Poncirus trifoliata …

Victims that were exposed to the chemical warfare agent sulfur mustard (SM) suffer from
chronic dermal and ocular lesions, severe pulmonary problems and cancer development. It …

The D2 dopamine receptor (DRD2) gene has garnered substantial attention as one of the
most extensively studied genes across various neuropsychiatric disorders. Since its initial …

The gastrointestinal (GI) tract is more vulnerable to effects by the outside environment, and
experiences oxidative stress. A wide diversity of GI disorders can be partially attributed to …

In this chapter, we present an overview of the available methods for DNA methylation
analysis with emphasis on particular features such as coverage and base resolution. These …