The role of mitochondria in rheumatic diseases

YLC Becker, B Duvvuri, PR Fortin, C Lood… - Nature Reviews …, 2022 - nature.com
The mitochondrion is an intracellular organelle thought to originate from endosymbiosis
between an ancestral eukaryotic cell and an α-proteobacterium. Mitochondria are the …

Immune disorders in hemodialysis patients

MR Sharif, Z Chitsazian, M Moosavian… - Iranian journal of …, 2015 - eprints.bmsu.ac.ir
Immunologically, end-stage renal disease is associated with some disorders in both innate
and adaptive immune system in such a form that there is a coexistence of both immune …

Oxidized but not native cardiolipin has pro-inflammatory effects, which are inhibited by Annexin A5

M Wan, X Hua, J Su, D Thiagarajan, AG Frostegård… - Atherosclerosis, 2014 - Elsevier
Objective Cardiolipin (CL) is a phospholipid with an unusual dimeric structure containing
four double-bonds and is easily oxidized. CL is present in mitochondria. Here we explored …

Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality

SK Samal, AR Qureshi, M Rahman… - Clinical & …, 2020 - academic.oup.com
The risk of premature death is high among patients on haemodialysis (HD patients). We
previously determined that immunoglobulin (Ig) M antibodies against phosphorylcholine …

Antibodies against native and oxidized cardiolipin and phosphatidylserine and phosphorylcholine in atherosclerosis development

AG Frostegård, J Su, X Hua, M Vikström, U de Faire… - PLoS …, 2014 - journals.plos.org
Background Antibodies against cardiolipin and phosphatidylserine (anti-CL and anti-PS) are
associated with thrombosis. In contrast, we determined that IgM antibodies against oxidized …

Antibodies against malondialdehyde in haemodialysis patients and its association with clinical outcomes: Differences between subclasses and isotypes

SK Samal, AR Qureshi, M Rahman… - Journal of Clinical …, 2020 - mdpi.com
Patients on haemodialysis (HD-patients) have an increased risk of premature death. Low
levels of IgM antibodies against malondialdehyde (anti-MDA) are associated with increased …

[PDF][PDF] Lin28a blunts cartilage loss in a mouse model of OA

R Phillips - Nature reviews. Rheumatology, 2022 - iranianra.ir
An analysis of primary and secondary care records for 22 million individuals in the UK found
an incidence rate of cardiovascular disease (CVD) of 23.3 events per 1,000 patient-years …

Immune mechanisms and potential immunological treatment in atherosclerosis

SK Samal - 2022 - search.proquest.com
Our immune system is an important and central part of the defence mechanisms of our body.
It carries out various important functions such as protecting us from invading …

Identification des cibles antigéniques d'origine mitochondriale, reconnues par les autoanticorps dans le lupus érythémateux disséminé

Y Becker - 2022 - corpus.ulaval.ca
Résumé Mitochondria are intracellular organelles in control of numerous biological
functions (eg, from energy supply to steroidogenesis and programmed cell death by …

Humoral immune response to carbamyl-epitopes in atherosclerosis

O Kummu - 2014 - oulurepo.oulu.fi
Tiivistelmä Proteiinien karbamylaatiota tapahtuu syanaatin vaikutuksesta. Sitä muodostuu
urean hajotessa tai myeloperoksidaasin katalysoimana tiosyanaatin hapettuessa. Low …