In this work, the influence of polymeric excipients (PEG6000, PEG400, PVPK25, and
HPMCE3) on thermodynamic phase behavior of active pharmaceutical ingredients …

The solubility of pharmaceutical cocrystals in aqueous solution is influenced by pH-
dependent dissociation and salt formation which complicates the design of cocrystal …

A simple model for viscosity based on residual entropy scaling is proposed in this study. The
thermodynamic model applied to calculate residual entropy is the Groupe Européen de …

In this work the ePC-SAFT equation of state is applied to model aqueous two-phase systems
(ATPS) containing polyethylene glycol (PEG) and one of 16 different inorganic salts at …

In the current study, the phase behaviour of indomethacin and poly (lactic-co-glycolic
acid)(PLGA) formulations was investigated as a function of the molecular weight and the …

In this work surface tensions are calculated by combining the Perturbed Chain Statistical
Associating Fluid Theory (PC-SAFT) with the Density Gradient Theory of inhomogeneous …

Purpose To analyze the dissolution mechanism of solid dispersions of poorly water-soluble
active pharmaceutical ingredients (APIs), to predict the dissolution profiles of the APIs and to …

A framework to self‐consistently combine a classical equation of state (EoS) and a
molecular force field to model polymers and polymer mixtures is presented. The statistical …

Prediction of compatibility of the active pharmaceutical ingredient (API) with the polymeric
carrier plays an essential role in designing drug delivery systems and estimating their long …

The purpose of this work is to increase the efficiency of the cocrystal formation process by
thermodynamic modeling using perturbed-chain statistical associating fluid theory (PC …