Background Genetic studies have provided ample evidence of the influence of non-coding
DNA polymorphisms on trait variance, particularly those occurring within transcription factor …

Epigenetic processes including RNA methylation, post-translational modifications, and non-
coding RNA expression have been associated with the heritable risks of systemic lupus …

Objectives Chamomile has long been used as a medicinal plant due to its antioxidative and
anti-inflammatory activity. Apigenin-7-O-glucoside (AG) is one of the major ethanol extract …

Background NLRP3 inflammasome has been implicated in the pathogenesis of systemic
lupus erythematosus (SLE). The activation of NLRP3 inflammasome results in the …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized
by a defect in immune tolerance and exacerbated by both the innate and adaptive arms of …

Cells of the innate immune system are rigged with sensors that detect nucleic acids derived
from microbes, especially viruses. It has become clear that these same sensors that respond …

Black women are disproportionately affected by systemic lupus erythematosus (SLE), a
chronic, potentially debilitating autoimmune disease, and they also experience more rapid …

Systemic lupus erythematosus (SLE), characterized by persistent inflammation, is a complex
autoimmune disorder that affects all organs, challenging clinical treatment. Dysbiosis of gut …

Lysosomes perform a range of functions, some of which, such as degradation, are common
to all cell types. Others, such as secretion or lysosomal exocytosis, are more specialised and …

Lonicera caerulea L. berry polyphenols (LCBP) are considered as major components for
bioactivity. This study aimed to clarify the molecular mechanisms by monitoring inflammatory …