Atopic Dermatitis (AD) is an extremely pruritic inflammatory skin disease that has a
worldwide prevalence of approximately 2.69%, with significant variability by country. 1 In the …

Basophils are rare cells in the peripheral blood which have the capability to infiltrate into the
skin. Invasion of basophils has been detected in pruritic skin diseases, including atopic …

Uremic pruritus, or chronic kidney disease-associated pruritus, is common, bothersome, and
sometimes debilitating in patients with chronic kidney disease or end-stage renal disease …

Background Ruxolitinib cream is a topical formulation of ruxolitinib, a Janus kinase (JAK)
1/JAK2 inhibitor. Objectives To report timing and magnitude of effect of ruxolitinib cream on …

Background Certain sensations are the secondary phenotypes of rosacea and affect
patients' quality of life. Transient receptor potential (TRP) channels may be involved in its …

Aedes aegypti (Ae. aegypti) saliva induces a variety of anti-inflammatory and
immunomodulatory activities. Interestingly, although it is known that mosquito bites cause …

Pruritus has an extensive impact on functional, social and psychosocial behaviour. The
association between pruritus and psychological well-being has mostly been studied among …

The interplay between the skin microbiome and its host is a complex facet of dermatological
health and has become a critical focus in the development of microbiome cosmetics. The …

Background: The Global Research on the Impact of Dermatological Diseases (GRIDD) team
is developing the new Patient-Reported Impact of Dermatological Diseases (PRIDD) …

Background Itch is a common symptom of skin diseases and significantly reduces patients'
quality of life. Melatonin has anti-inflammatory and antioxidant effects. Our study examined …