Mechanisms and functions of long non-coding RNAs at multiple regulatory levels

X Zhang, W Wang, W Zhu, J Dong, Y Cheng… - International journal of …, 2019 - mdpi.com
Long non-coding (lnc) RNAs are non-coding RNAs longer than 200 nt. lncRNAs primarily
interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression …

[HTML][HTML] Long non-coding RNAs: the regulatory mechanisms, research strategies, and future directions in cancers

N Gao, Y Li, J Li, Z Gao, Z Yang, Y Li, H Liu… - Frontiers in …, 2020 - frontiersin.org
The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …

The emerging role of lncRNAs in cancer

M Huarte - Nature medicine, 2015 - nature.com
It is increasingly evident that many of the genomic mutations in cancer reside inside regions
that do not encode proteins. However, these regions are often transcribed into long …

[HTML][HTML] N6-methylandenosine-related lncRNAs are potential biomarkers for predicting the overall survival of lower-grade glioma patients

Z Tu, L Wu, P Wang, Q Hu, C Tao, K Li… - Frontiers in cell and …, 2020 - frontiersin.org
The prognostic value of N6-methylandenosine-related long non-coding RNAs (m6A-related
lncRNAs) was investigated in 646 lower-grade glioma (LGG) samples from The Cancer …

Diverse applications of nanomedicine

B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves… - ACS …, 2017 - ACS Publications
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

Long non-coding RNAs and complex diseases: from experimental results to computational models

X Chen, CC Yan, X Zhang, ZH You - Briefings in bioinformatics, 2017 - academic.oup.com
LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …

Roles and regulation of long noncoding RNAs in hepatocellular carcinoma

LJ Lim, SYS Wong, F Huang, S Lim, SS Chong, LL Ooi… - Cancer Research, 2019 - AACR
Next-generation sequencing has uncovered thousands of long noncoding RNAs (lncRNA).
Many are reported to be aberrantly expressed in various cancers, including hepatocellular …

[HTML][HTML] LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells

W Qi, Z Li, L Xia, J Dai, Q Zhang, C Wu, S Xu - Scientific Reports, 2019 - nature.com
Ferroptosis is a non-apoptotic, iron-dependent oxidative form of cell death that is specifically
induced by erastin in RAS mutant cancer cells. Ferroptotic cell death is the result of …

Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

In vitro and in vivo RNA inhibition by CD9-HuR functionalized exosomes encapsulated with miRNA or CRISPR/dCas9

Z Li, X Zhou, M Wei, X Gao, L Zhao, R Shi, W Sun… - Nano …, 2018 - ACS Publications
In vitro and in vivo delivery of RNAs of interest holds promise for gene therapy. Recently,
exosomes are considered as a kind of rational vehicle for RNA delivery, especially miRNA …