Redefining preeclampsia using placenta-derived biomarkers

AC Staff, SJ Benton, P von Dadelszen, JM Roberts… - …, 2013 - Am Heart Assoc
Compared with the nonpregnant state, normal pregnancy is characterized by a low-grade
systemic inflammatory response, which is further enhanced in preeclampsia. 17 It is …

Maternal omega-3 nutrition, placental transfer and fetal brain development in gestational diabetes and preeclampsia

PP Devarshi, RW Grant, CJ Ikonte, S Hazels Mitmesser - Nutrients, 2019 - mdpi.com
Omega-3 fatty acids, particularly docosahexaenoic fatty acid (DHA), are widely recognized
to impact fetal and infant neurodevelopment. The impact of DHA on brain development, and …

Evidence based recommendations for an optimal prenatal supplement for women in the US: vitamins and related nutrients

JB Adams, JK Kirby, JC Sorensen, EL Pollard… - Maternal Health …, 2022 - Springer
The blood levels of most vitamins decrease during pregnancy if un-supplemented, including
vitamins A, C, D, K, B1, B3, B5, B6, folate, biotin, and B12. Sub-optimal intake of vitamins …

Is supplementation with micronutrients still necessary during pregnancy? A review

S Santander Ballestín, MI Giménez Campos… - Nutrients, 2021 - mdpi.com
Introduction: Proper nutrition during pregnancy is important to prevent nutritional imbalances
that interfere with pregnancy. Micronutrients play critical roles in embryogenesis, fetal …

[HTML][HTML] Is supplementation with micronutrients still necessary during pregnancy? A review

SS Ballestín, MIG Campos, JB Ballestín… - Nutrients, 2021 - ncbi.nlm.nih.gov
Introduction: Proper nutrition during pregnancy is important to prevent nutritional imbalances
that interfere with pregnancy. Micronutrients play critical roles in embryogenesis, fetal …

Angiogenic and antiangiogenic factors in preeclampsia

FR Helmo, AMM Lopes, ACDM Carneiro… - … -Research and Practice, 2018 - Elsevier
Background Pre-eclampsia is a multifactorial hypertensive disorder that is triggered by
placental insufficiency and that accounts for up to 15% of maternal deaths. In normal …

Increased oxidative stress from early pregnancy in women who develop preeclampsia

V D'Souza, A Rani, V Patil, H Pisal… - Clinical and …, 2016 - Taylor & Francis
Preeclampsia (PE) is a pregnancy-specific disorder, defined as new onset of maternal
hypertension and proteinuria after 20 weeks of gestation. Our earlier study has shown …

Global DNA methylation patterns in placenta and its association with maternal hypertension in pre-eclampsia

A Kulkarni, P Chavan-Gautam, S Mehendale… - DNA and cell …, 2011 - liebertpub.com
Maternal nutrition is an important determinant of one-carbon metabolism that lies at the heart
of intrauterine epigenetic programming. Exchange of nutrients and other vital molecules …

Biochemical tests of placental function versus ultrasound assessment of fetal size for stillbirth and small‐for‐gestational‐age infants

AEP Heazell, DJL Hayes, M Whitworth… - Cochrane Database …, 2019 - cochranelibrary.com
Background Stillbirth affects 2.6 million pregnancies worldwide each year. Whilst the
majority of cases occur in low‐and middle‐income countries, stillbirth remains an important …

Differential placental methylation and expression of VEGF, FLT- 1 and KDR genes in human term and preterm preeclampsia

DP Sundrani, US Reddy, AA Joshi, SS Mehendale… - Clinical …, 2013 - Springer
Background Preeclampsia, a pregnancy complication of placental origin is associated with
altered expression of angiogenic factors and their receptors. Recently, there is considerable …