Recent evidence shows that transplantation of neural stem/precursor cells may protect the
central nervous system from inflammatory damage through a'bystander'mechanism that is …

The metalloproteinase and major amyloid precursor protein (APP) α-secretase candidate
ADAM10 is responsible for the shedding of proteins important for brain development, such …

Spinal cord injury results in the permanent loss of function, causing enormous personal,
social and economic problems. Even though neural regeneration has been proven to be a …

Cardiac stem cells (CSCs) have been identified in the adult heart, but the microenvironment
that protects the slow-cycling, undifferentiated, and self-renewing CSCs remains to be …

Deciphering the factors that regulate human neural stem cells will greatly aid in their use as
models of development and as therapeutic agents. The extracellular matrix (ECM) is a …

Cortical expansion and folding are often linked to the evolution of higher intelligence, but
molecular and cellular mechanisms underlying cortical folding remain poorly understood …

Transcription factors and signaling molecules are well‐known regulators of stem cell identity
and behavior; however, increasing evidence indicates that environmental cues contribute to …

After the initial reports of free-floating cultures of neural stem cells termed neurospheres (1,
2), a wide array of studies using this promising culture system emerged. In theory, this was a …

The mammalian cerebral cortex is the pinnacle of brain evolution, reaching its maximum
complexity in terms of neuron number, diversity and functional circuitry. The emergence of …

Nowadays, the research on NPC transplantation in neurological disorders is advancing on
two different fronts: on one hand, recent preclinical data are uncovering the molecular basis …