Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …

The optimal treatment for complex fractures and large bone defects is an important unsolved
issue in orthopedics and related specialties. Approximately 5–10% of fractures fail to heal …

Polycystic ovary syndrome (PCOS) is the most common hormonal imbalance disease in
reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian …

Obesity, manifested by increased adiposity, represents a main cause of morbidity in the
developed countries, causing increased risk of insulin resistance and type 2 diabetes …

Chronic inflammation plays an important role in the development of metabolic diseases.
These include obesity, type 2 diabetes mellitus, and metabolic dysfunction-associated fatty …

Highlights•Immunometabolism of the adipose tissue affects insulin resistance and
obesity.•Type 2 immune response protects against diet-induced obesity.•Cytokines …

Non-alcoholic fatty liver disease (NAFLD) constitutes a spectrum of disease states
characterized by hepatic steatosis and is closely associated to obesity and the metabolic …

Abstract In mammals, interleukin (IL)-17 cytokines are produced by innate and adaptive
lymphocytes. However, the IL-17 family has widespread expression throughout evolution …

Interleukin 17A (IL-17A) is one of the currently known six members of the IL-17 cytokine
family and is implicated in immune responses to infectious pathogens and in the …

Obesity is associated with low-grade chronic inflammation. Indeed, adipose tissues (AT) in
obese individuals are the former site of progressive infiltration by pro-inflammatory immune …