Osteoporosis is characterized by low bone mineral density and structural deterioration of
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …

Background Many studies have reported associations between estrogen receptor (ER) gene
polymorphisms and postmenopausal osteoporosis (PMOP) risk and bone mineral density …

Loading-related changes in gene expression in resident cells in the tibia of female mice in
the contexts of normality (WT), estrogen deficiency (WT-OVX), absence of estrogen receptor …

It has been suggested that the estrogen receptor alpha (ERα) and vitamin D receptor (VDR)
genes as possibly implicated in reduced bone mineral density (BMD) in osteoporosis. The …

Osteoporosis is an important and complex disorder that is highly prevalent worldwide. This
disease poses a major challenge to modern medicine and its treatment is associated with …

To probe the importance of the heterocyclic core of estrogen receptor (ER) ligands, we
prepared a series of thiophene-core ligands by Suzuki cross-coupling of aryl boronic acids …

Background: In Europeans and populations of European origin, several osteoporosis
susceptibility genes, including ZBTB40, RANK, RANKL, OPG, MHC, and ESR1, were …

Identification of risk factors for osteoporosis has been essential for understanding the
development of osteoporosis. The collagen type I alpha1 (COL1A1) gene is suggested to be …

Osteoporosis, which is characterised by reduced bone mineral density (BMD) and an
increased risk of fragility fractures, is the result of a complex interaction between …

Background A number of studies have examined the association between estrogen receptor
alpha (ESR-α) gene polymorphisms and bone mineral density (BMD), but previous studies …