DNA microarrays are widely used to investigate gene expression. Even though the classical
analysis of microarray data is based on the study of differentially expressed genes, it is well …

Glioblastoma (GBM) is one of the most malignant and intractable central nervous system
tumors with high recurrence, low survival rate, and poor prognosis. Despite the advances of …

Depression has become one of the most crucial public health issues, threatening the quality
of life of over 300 million people throughout the world. Nevertheless, the clinical diagnosis of …

Bipolar disorder (BD) is a major and highly heritable mental illness with severe psychosocial
impairment, but its etiology and pathogenesis remains unclear. This study aimed to identify …

The protozoan parasite Perkinsus marinus causes Dermo disease in eastern oysters,
Crassostrea virginica, and can suppress apoptosis of infected hemocytes using incompletely …

Background The coronavirus disease (COVID-19) pandemic has posed a significant
challenge for global health systems. Increasing evidence shows that asthma phenotypes …

Embryogenesis is a complex phase of conifer development involving hundreds of genes,
and a proper understanding of this process is critical not only to produce embryos with …

Small cell lung cancer (SCLC) is an aggressive disease and challenging to treat due to its
mixture of transcriptional subtypes and subtype transitions. Transcription factor (TF) …

Stripe rust (Sr), caused by Puccinia striiformis f. sp. tritici (Pst), is the most devastating
disease that poses serious threat to the wheat-growing nations across the globe …

Tomato fruit ripening is triggered by the demethylation of key genes, which alters their
transcriptional levels thereby initiating and propagating a cascade of physiological events …