Stabilized COre gene and Pathway Election uncovers pan-cancer shared pathways and a cancer-specific driver
Approaches systematically characterizing interactions via transcriptomic data usually follow
two systems:(i) coexpression network analyses focusing on correlations between genes and …
two systems:(i) coexpression network analyses focusing on correlations between genes and …
Network as a language for precision medicine
L Farina - Annali dell'Istituto Superiore di Sanità, 2021 - annali.iss.it
The article takes as a starting point the observation of a deep and long-standing gap
between the views of biologists/physicians and that of physicists/data scientists when …
between the views of biologists/physicians and that of physicists/data scientists when …
[HTML][HTML] Genome-wide DNA methylation and RNA-seq analyses identify genes and pathways associated with doxorubicin resistance in a canine diffuse large B-cell …
CH Hsu, H Tomiyasu, CH Liao, CS Lin - Plos one, 2021 - journals.plos.org
Doxorubicin resistance is a major challenge in the successful treatment of canine diffuse
large B-cell lymphoma (cDLBCL). In the present study, MethylCap-seq and RNA-seq were …
large B-cell lymphoma (cDLBCL). In the present study, MethylCap-seq and RNA-seq were …
[HTML][HTML] Transcriptome analysis revealed hub genes for muscle growth in Indian major carp, Catla catla (Hamilton, 1822)
V Mohindra, LM Chowdhury, N Chauhan, RK Maurya… - Genomics, 2022 - Elsevier
Catla (Catla catla) is the fastest growing Indian major carp species and forms an important
component of the freshwater aquaculture systems in the Indian sub-continent. The molecular …
component of the freshwater aquaculture systems in the Indian sub-continent. The molecular …
[HTML][HTML] Bioinformatics and network biology approach to identifying type 2 diabetes genes and pathways that influence the progression of breast cancer
Breast cancer is the second most prevalent malignancy affecting women. Postmenopausal
women breast tumor is one of the top causes of death in women, accounting for 23% of …
women breast tumor is one of the top causes of death in women, accounting for 23% of …
[HTML][HTML] Identification of key genes as early warning signals of acute myocardial infarction based on weighted gene correlation network analysis and dynamic network …
C Song, Z Qiao, L Chen, J Ge, R Zhang… - Frontiers in …, 2022 - frontiersin.org
Purpose The specific mechanisms and biomarkersunderlying the progression of stable
coronary artery disease (CAD) to acute myocardial infarction (AMI) remain unclear. The …
coronary artery disease (CAD) to acute myocardial infarction (AMI) remain unclear. The …
scGIR: deciphering cellular heterogeneity via gene ranking in single-cell weighted gene correlation networks
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for investigating
cellular heterogeneity through high-throughput analysis of individual cells. Nevertheless …
cellular heterogeneity through high-throughput analysis of individual cells. Nevertheless …
The GRN concept as a guide for evolutionary developmental biology
Organismal phenotypes result largely from inherited developmental programs, usually
executed during embryonic and juvenile life stages. These programs are not blank slates …
executed during embryonic and juvenile life stages. These programs are not blank slates …
[HTML][HTML] Transcriptional modulation of the hippo signaling pathway by drugs used to treat bipolar disorder and schizophrenia
B Panizzutti, CC Bortolasci, B Spolding… - International Journal of …, 2021 - mdpi.com
Recent reports suggest a link between positive regulation of the Hippo pathway with bipolar
disorder (BD), and the Hippo pathway is known to interact with multiple other signaling …
disorder (BD), and the Hippo pathway is known to interact with multiple other signaling …
[HTML][HTML] Chromosome groups 5, 6 and 7 harbor major quantitative trait loci controlling root traits in bread wheat (Triticum aestivum L.)
Identifying genomic regions for root traits in bread wheat can help breeders develop climate-
resilient and high-yielding wheat varieties with desirable root traits. This study used the …
resilient and high-yielding wheat varieties with desirable root traits. This study used the …