Metal contamination issues are becoming increasingly common in India and elsewhere, with
many documented cases of metal toxicity in mining industries, foundries, smelters, coal …

The concept of 'lifestyle 'includes different factors such as nutrition, behavior, stress, physical
activity, working habits, smoking and alcohol consumption. Increasing evidence shows that …

Associations between modifiable exposures and disease seen in observational
epidemiology are sometimes confounded and thus misleading, despite our best efforts to …

CpG methylation in vertebrates correlates with alterations in chromatin structure and gene
silencing 1, 2, 3, 4. Differences in DNA-methylation status are associated with imprinting …

Azacytidine was first synthesized almost 40 years ago. It was demonstrated to have a wide
range of anti-metabolic activities when tested against cultured cancer cells and to be an …

Methionine is an essential amino acid with many key roles in mammalian metabolism such
as protein synthesis, methylation of DNA and polyamine synthesis. Restriction of methionine …

The present system of radiation protection assumes that exposure at low doses and/or low
dose-rates leads to health risks linearly related to the dose. They are evaluated by a …

Folate is a water-soluble B-vitamin and enzymatic cofactor that is necessary for the synthesis
of purine and thymidine nucleotides and for the synthesis of methionine from homocysteine …

Folate plays a critical role in the prevention of uracil incorporation into DNA and
hypomethylation of DNA. This activity is compromised when vitamin B12 concentration is …

Folate, a water-soluble B vitamin, has recently garnered much attention because of its
purported role in the pathogenesis of cardiovascular disease, 1–4 neural tube defects, 5–7 …