Sleep disorders affect many people worldwide and can accompany neurodegenerative and
psychiatric diseases. Sleep may be altered before the clinical manifestations of some of …

Genetics and omics studies of Alzheimer's disease and other dementia subtypes enhance
our understanding of underlying mechanisms and pathways that can be targeted. We …

Sleep and/or wake cycle alterations are common in neurodegenerative diseases (ND). Our
aim was to determine whether there is a causal relationship between sleep and/or wake …

Abstract Background Until now, Mendelian randomization (MR) studies have investigated
the causal association of risk factors with Alzheimer's disease (AD) using large-scale AD …

Sleep disorders are very often underestimated and, consequently, not treated with due
priority. Common sleep disorders include insomnia disorders, sleep-related breathing …

This review explores the criteria used for the selection of genetic instruments of sleep traits
in the context of Mendelian randomisation studies. This work was motivated by the fact that …

Background Observational studies have reported maternal short/long sleep duration to be
associated with adverse pregnancy and perinatal outcomes. However, it remains unclear …

Sleep disorders frequently result in poor memory, attention deficits, as well as a worse
prognosis for neurodegenerative changes, such as Alzheimer's disease. The purpose of this …

Late-onset Alzheimer's disease (AD) is associated with sleep-related phenotypes (SRPs).
The fact that whether they share a common genetic etiology remains largely unknown. We …

Sleep occurs universally and is a biological necessity for human functioning. The
consequences of diminished sleep quality impact physical and physiological systems such …