Myosin-1D (myo1D) is important for Drosophila left-right asymmetry, and its effects are
modulated by myosin-1C (myo1C). De novo expression of these myosins in nonchiral …

As Nature's version of machine learning, evolution has solved many extraordinarily complex
problems, none perhaps more remarkable than learning to harness an increase in chemical …

Myosins are required for clathrin-mediated endocytosis, but their precise molecular roles in
this process are not known. This is, in part, because the biophysical properties of the …

Biological motors function at the interface of biology, physics, and chemistry, and it remains
unsettled what rules from which disciplines account for how these motors work. Myosin …

Almost every model of muscle contraction in the literature to date is a molecular power
stroke model, even though this corpuscular mechanism is opposed by centuries of science …

The grafting of a drug molecule, ie, geldanamycin (GA) onto polyethyleneimine (PEI)-coated
magnetic nanoparticle produces a novel composite, GA@ Fe 3 O 4–NH 2. The composite is …

Actin-myosin interactions form the basis of the force-producing contraction cycle within the
sarcomere, serving as the primary mechanism for muscle contraction. Post-translational …

Accurate models of muscle contraction are important for understanding both muscle
performance and the therapeutics that enhance physiological function. However, models are …

Introduction Myosin II has been investigated with optical trapping, but single motor-filament
assay arrangements are not reflective of the complex cellular environment. To understand …

Molecular motors play a central role in many biological processes, ranging from pumping
blood and breathing to growth and wound healing. Through motor-catalyzed chemical …