Skeletal muscle damaged by injury or by degenerative diseases such as muscular
dystrophy is able to regenerate new muscle fibers. Regeneration mainly depends upon …

Tissue and organ regeneration proceed in a coordinated manner to restore proper function
after trauma. Vertebrate skeletal muscle has a remarkable ability to regenerate after …

Cells derived from blood vessels of human skeletal muscle can regenerate skeletal muscle,
similarly to embryonic mesoangioblasts. However, adult cells do not express endothelial …

Duchenne muscular dystrophy remains an untreatable genetic disease that severely limits
motility and life expectancy in affected children. The only animal model specifically …

Abstract Background Term Amniotic membrane (AM) is a very attractive source of
Mesenchymal Stem Cells (MSCs) due to the fact that this fetal tissue is usually discarded …

A major impediment to the successful application of gene therapy for the treatment of a
range of diseases is not a paucity of therapeutic genes, but the lack of an efficient non‐toxic …

Adipose-tissue-derived mesenchymal stem cells can be directed towards a myogenic
phenotype in vitro by the addition of specific inductive media. However, the ability of these or …

Muscular dystrophies primarily affect skeletal muscle. Mutations in a large number of genes,
mainly encoding cytoskeletal proteins, cause different forms of dystrophy that compromise …

Mesenchymal stromal cells (MSCs) are the leading cell candidates in the field of
regenerative medicine. These cells have also been successfully used to improve skeletal …

Over the past century, understanding the mechanisms underlying muscle fatigue and
weakness has been the focus of much investigation. However, the dominant theory in the …