The genetic and molecular pathogenesis of myelodysplastic syndromes

RM Shallis, R Ahmad, AM Zeidan - European journal of …, 2018 - Wiley Online Library
Myelodysplastic syndromes (MDS) comprise a diverse group of clonal and malignant
myeloid disorders characterized by ineffective hematopoiesis, resultant peripheral …

Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts

E Papaemmanuil, M Cazzola… - … England Journal of …, 2011 - Mass Medical Soc
Background Myelodysplastic syndromes are a diverse and common group of chronic
hematologic cancers. The identification of new genetic lesions could facilitate new …

Prognostic markers of myelodysplastic syndromes

YA Veryaskina, SE Titov, IB Kovynev, TI Pospelova… - Medicina, 2020 - mdpi.com
Myelodysplastic syndrome (MDS) is a clonal disease characterized by multilineage
dysplasia, peripheral blood cytopenias, and a high risk of transformation to acute myeloid …

[HTML][HTML] A prospective multicenter observational study of decitabine treatment in Korean patients with myelodysplastic syndrome

JH Lee, JH Jang, J Park, S Park, YD Joo, YK Kim… - …, 2011 - ncbi.nlm.nih.gov
A prospective multicenter observational study of decitabine treatment in Korean patients with
myelodysplastic syndrome - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Is International Prognostic Scoring System (IPSS) still standard in predicting prognosis in patients with myelodysplastic syndrome? External validation of the WHO …

MJ Park, HJ Kim, SH Kim, DH Kim… - European journal of …, 2008 - Wiley Online Library
Background: This study was undertaken to evaluate the prognostic value of the WHO
Classification‐Based Prognostic Scoring System (WPSS) and to compare it with that of the …

Decitabine for treatment of myelodysplastic syndromes in Chinese patients: an open-label, phase-3b study

D Wu, X Du, J Jin, Z Xiao, Z Shen, Z Shao, X Li… - Advances in …, 2015 - Springer
Introduction The objective of this study was to evaluate the efficacy and safety of decitabine
in Chinese patients with myelodysplastic syndrome (MDS). Methods Patients (≥ 18 years) …

Decreased incidence of febrile episodes with antibiotic prophylaxis in the treatment of decitabine for myelodysplastic syndrome

JH Lee, KH Lee, JH Lee, DY Kim, SH Kim, SN Lim… - Leukemia research, 2011 - Elsevier
We analyzed the role of antibiotic prophylaxis during decitabine treatment for MDS. The
primary endpoint was the incidence of febrile episodes. The total number of decitabine …

Acquired elliptocytosis as a manifestation of myelodysplastic syndrome with ring sideroblasts and multilineage dysplasia

JD Kjelland, DM Dwyre… - Case Reports in …, 2017 - Wiley Online Library
Acquired elliptocytosis is a known but rarely described abnormality in the myelodysplastic
syndromes (MDS). Here we report the case of an elderly male who was admitted to the …

Unique cytogenetic features of primary myelodysplastic syndromes in Chinese patients

L Li, XP Liu, L Nie, MH Yu, Y Zhang, TJ Qin, ZJ Xiao - Leukemia research, 2009 - Elsevier
Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid neoplasms.
Chromosomal abnormalities have been detected in 40–70% patients with primary MDS and …

Prognoses of MDS subtypes RARS, RCMD and RCMD-RS are comparable but cytogenetics separates a subgroup with inferior clinical course

U Bacher, W Kern, T Alpermann, S Schnittger… - Leukemia research, 2012 - Elsevier
In 2008, the WHO combined the former categories RCMD (refractory cytopenia with
multilineage dysplasia) and RCMD-RS (ring sideroblasts≥ 15%). We studied the clinical …