Background Acquired deficiency of ADAMTS13 causes a rare and life‐threatening disorder
called thrombotic thrombocytopenic purpura (TTP). Several studies have shown that …

Resurgent mumps outbreaks have raised questions about the current efficacy of mumps
vaccines. We have applied immunoinformatics techniques based on principal component …

Background The development of an efficient vaccine and broadly cross-neutralizing
antibodies of hepatitis C virus (HCV) remains a priority. The heavily glycosylated viral …

The mannose receptor (MR) is an important component of the immune system and
understanding the structural and conformational characteristics of this receptor is a key …

ILs are part of the immune system and are involved in multiple biological activities. ILs have
been shown to evolve under positive selection; however, little information exists regarding …

Clinical evaluation of comparative immunogenicity represents an important component of
the European Union regulatory review process for candidate biosimilar products. The …

Preclinical animal studies convincingly demonstrate that tumor immunity to self-antigens can
be actively induced and can translate into effective anti-tumor responses. Among the most …

The main function of carbonic anhydrases is to regulate acid-base balance. In the present
study, the zebrafish CA15b sequence was identified from the National Center for …

Chikungunya virus (CHIKV) infection has caught attention yet again as it rages around the
globe affecting millions of people. The virus caused epidemic outbreaks affecting more than …

Calreticulin (CRT), a luminal resident calcium-binding glycoprotein of the cell, is a tumor-
associated antigen involved in tumorigenesis and also an autoantigen targeted by …