Sepsis and septic shock
Sepsis is a common condition that is associated with unacceptably high mortality and, for
many of those who survive, long-term morbidity. Increased awareness of the condition …
many of those who survive, long-term morbidity. Increased awareness of the condition …
Procalcitonin as a diagnostic marker for sepsis: a systematic review and meta-analysis
C Wacker, A Prkno, FM Brunkhorst… - The Lancet infectious …, 2013 - thelancet.com
Background Procalcitonin is a promising marker for identification of bacterial infections. We
assessed the accuracy and clinical value of procalcitonin for diagnosis of sepsis in critically …
assessed the accuracy and clinical value of procalcitonin for diagnosis of sepsis in critically …
The surgical infection society revised guidelines on the management of intra-abdominal infection
JE Mazuski, JM Tessier, AK May, RG Sawyer… - Surgical …, 2017 - liebertpub.com
Background: Previous evidence-based guidelines on the management of intra-abdominal
infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and …
infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and …
Combination therapy for treatment of infections with gram-negative bacteria
PD Tamma, SE Cosgrove… - Clinical microbiology …, 2012 - Am Soc Microbiol
Combination antibiotic therapy for invasive infections with Gram-negative bacteria is
employed in many health care facilities, especially for certain subgroups of patients …
employed in many health care facilities, especially for certain subgroups of patients …
De-escalation of empirical therapy is associated with lower mortality in patients with severe sepsis and septic shock
J Garnacho-Montero, A Gutiérrez-Pizarraya… - Intensive care …, 2014 - Springer
Purposes We set out to assess the safety and the impact on in-hospital and 90-day mortality
of antibiotic de-escalation in patients admitted to the ICU with severe sepsis or septic shock …
of antibiotic de-escalation in patients admitted to the ICU with severe sepsis or septic shock …
The diagnostic accuracy of procalcitonin and C‐reactive protein for sepsis: a systematic review and meta‐analysis
M Tan, Y Lu, H Jiang, L Zhang - Journal of cellular biochemistry, 2019 - Wiley Online Library
Background The objective of this study was to systematically evaluate the clinical value of
procalcitonin and C‐reactive protein in the diagnosis of adult patients with sepsis. Method …
procalcitonin and C‐reactive protein in the diagnosis of adult patients with sepsis. Method …
Evaluation of the FilmArray blood culture identification panel: results of a multicenter controlled trial
H Salimnia, MR Fairfax, PR Lephart… - Journal of clinical …, 2016 - Am Soc Microbiol
Sepsis is a major cause of morbidity, mortality, and increased medical expense. Rapid
diagnosis improves outcomes and reduces costs. The FilmArray blood culture identification …
diagnosis improves outcomes and reduces costs. The FilmArray blood culture identification …
Gram-positive toxic shock syndromes
E Lappin, AJ Ferguson - The Lancet infectious diseases, 2009 - thelancet.com
Toxic shock syndrome (TSS) is an acute, multi-system, toxin-mediated illness, often resulting
in multi-organ failure. It represents the most fulminant expression of a spectrum of diseases …
in multi-organ failure. It represents the most fulminant expression of a spectrum of diseases …
Sepsis: mechanisms of bacterial injury to the patient
H Minasyan - Scandinavian journal of trauma, resuscitation and …, 2019 - Springer
In bacteremia the majority of bacterial species are killed by oxidation on the surface of
erythrocytes and digested by local phagocytes in the liver and the spleen. Sepsis-causing …
erythrocytes and digested by local phagocytes in the liver and the spleen. Sepsis-causing …
Programas de optimización de uso de antimicrobianos (PROA) en hospitales españoles: documento de consenso GEIH-SEIMC, SEFH y SEMPSPH
J Rodríguez-Baño, JR Pano-Pardo… - … y Microbiología Clínica, 2012 - Elsevier
Los antimicrobianos son fármacos distintos al resto. Su eficacia en la reducción de la
morbilidad y la mortalidad es muy superior a la de otros grupos de medicamentos. Por otra …
morbilidad y la mortalidad es muy superior a la de otros grupos de medicamentos. Por otra …