Highlights•Experimental advances allow us to see long-term drift in neural
representations.•Drift challenges classical notions of receptive fields and engrams.•Drift is …

In the hippocampus, spatial maps are formed by place cells while contextual memories are
thought to be encoded as engrams,,,,–. Engrams are typically identified by expression of the …

Long-lasting synaptic changes within the neuronal network mediate memory. Neurons
bearing such physical traces of memory (memory engram cells) are often equated with …

Change is ubiquitous in living beings. In particular, the connectome and neural
representations can change. Nevertheless, behaviors and memories often persist over long …

Mutations in the X-linked gene MECP2 cause Rett syndrome, a progressive neurological
disorder in which children develop normally for the first one or two years of life before …

In Alzheimer's disease (AD), hippocampus-dependent memories underlie an extensive
decline. The neuronal ensemble encoding a memory, termed engram, is partially …

We review the literature on systems consolidation by providing a brief history of the field to
place the current research in proper perspective. We cover the literature on both humans …

Memories are encoded by memory traces or engrams, represented within subsets of
neurons that are synchronously activated during learning. However, the molecular …

Touch can positively influence cognition and emotion, but the underlying mechanisms
remain unclear. Here, we report that tactile experience enrichment improves memory and …

Stress exposure impairs brain structure and function, resulting in cognitive deficits and
increased risk for psychiatric disorders such as depression, schizophrenia, anxiety and post …