Heme oxygenases (HOs) act on heme degradation to produce carbon monoxide (CO), free
iron, ferritin, and biliverdin. Upregulation of cellular HO-1 levels is signature of oxidative …

Oxidative stress (OS) is created by an imbalance between reactive oxygen species and
antioxidant levels. OS promotes inflammation and is associated with many diseases, such …

Follicular thyroid cancer (FTC) is a highly aggressive type of endocrine malignancy. It is
necessary to investigate the mechanisms of tumorigenesis and therapeutic pathways in …

Quantum biological tunnelling for electron transfer is involved in controlling essential
functions for life such as cellular respiration and homoeostasis. Understanding and …

Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid
peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight …

In the tumor microenvironment (TME), tumor-associated macrophages (TAMs) are the most
abundant immune cells, which act as a key regulator in tumorigenesis and progression …

Transplanting aged human skin onto young SCID/beige mice morphologically rejuvenates
the xenotransplants. This is accompanied by angiogenesis, epidermal repigmentation, and …

Gastrointestinal cancers, particularly colorectal cancer, are mainly influenced by the dietary
factor. A diet rich in fruits and vegetables can help to reduce the incidence of colorectal …

Neuroendocrine prostate carcinoma (NEPC) accounts for less than 1% of prostate
neoplasms and has extremely poorer prognosis than the typical androgen receptor pathway …

Primary tumors evolve metabolic mechanisms favoring glycolysis for adenosine
triphosphate (ATP) generation and antioxidant defenses. In contrast, metastatic cells …