Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Neural stem cells (NSCs) have garnered significant scientific and commercial interest in the
last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes …

Neurogenesis is maintained in the mammalian brain throughout adulthood in two main
regions: the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone …

Glial cells are an essential component of the nervous system of vertebrates and
invertebrates. In the human brain, glia are as numerous as neurons, yet the importance of …

Astrocytes are essential for proper regulation of the central nervous system (CNS).
Importantly, these cells are highly secretory in nature. Indeed they can release hundreds of …

Traumatic Brain Injury (TBI) represents a significant health concern, necessitating advanced
therapeutic interventions. This detailed review explores the critical roles of astrocytes, key …

Cell transplantation is an attractive treatment strategy for a variety of brain disorders, as it
promises to replenish lost functions and rejuvenate the brain. In particular, transplantation of …

The master neuronal transcription factor NeuroD1 can directly reprogram astrocytes into
induced neurons (iNeurons) after stroke. Using viral vectors to drive ectopic ND1 expression …

Echinoderms are a phylum of marine deterostomes with a range of interesting biological
features. One remarkable ability is their impressive capacity to regenerate most of their adult …

For more than 10 years, gene therapy for neurological diseases has experienced intensive
research growth and more recently therapeutic interventions for multiple indications …