Alzheimer's disease (AD) is a chronic neurodegenerative disease, with the characteristics of
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …

Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

Skeletal muscle atrophy is prevalent in a myriad of pathological conditions, such as
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …

Human beings lead largely sedentary lives. From an evolutionary perspective, such lifestyle
is not beneficial to health. Exercise can promote many enabling pathways, particularly …

Skeletal muscle health and function are important determinants of systemic metabolic
homeostasis and organism-wide responses, including disease outcome. While it is well …

Osteoarthritis is a chronic degenerative musculoskeletal disease characterized by
pathological changes in joint structures along with the incidence of which increases with …

Aerobic exercise has emerged as a promising intervention for mild cognitive impairment
(MCI), a precursor to dementia. The therapeutic benefits of aerobic exercise are …

Parkinson's disease with cognitive impairment (PD-CI) results in several clinical outcomes
for which specific treatment is lacking. Although the pathogenesis of PD-CI has not yet been …

Myokines are peptides and proteins secreted by skeletal muscle cells, into the interstitium, or
in the blood. Their regulation may be dependent or independent of muscle contraction to …

Genetically proxied lean mass and risk of Alzheimer’s disease: mendelian randomisation study
- PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …