Platinum-based anticancer drugs currently available in the market are associated with
severe side effects. Therefore, extensive research has been performed to design and …

The great advances in the studies on metal complexes for the treatment of different cancer
forms, starting from the pioneering works on platinum derivatives, have fostered an …

We investigated the use of amphiphilic, protease-cleavable peptides as encapsulation
moieties for hydrophobic metallodrugs, in order to enhance their bioavailability and …

Cyclometalated Ir (III) complexes hold great promise as an alternative to platinum
metallodrugs for the therapy and diagnosis of cancer. However, their low aqueous solubility …

Effective anticancer therapies are required to overcome limitations of conventional
chemotherapy. Current study demonstrated successful preparation of stable gold …

Every year, more Cu (II) complexes are proven to be biologically active species, but very few
are developed as drugs or entered in clinical trials. This is due to their poor water solubility …

Mesoporous silica nanoparticles (MSN) have been functionalized with the polyamino ligand
N 1-(3-trimethoxysilylpropyl) diethylenetriamine to give the material MSN-DETATMS (M1) …

Metals are indispensable for the life of all organisms, and their dysregulation leads to
various disorders due to the disruption of their homeostasis. Nowadays, various transition …

Two types of ruthenium (II) complexes containing 1, 2, 4-triazolo [1, 5-a] pyrimidines of the
general formulas [RuCl2 (dmso) 3 (L)]((1)–(3)) and [RuCl2 (dmso) 2 (L) 2]((4)–(6)), where L …

Nanotechnology-based approaches for targeting the delivery and controlled release of
metal-based therapeutic agents have revealed significant potential as tools for enhancing …