Interleukin-6 interweaves the bone marrow microenvironment, bone loss, and multiple myeloma

D Harmer, C Falank, MR Reagan - Frontiers in endocrinology, 2019 - frontiersin.org
The immune system is strongly linked to the maintenance of healthy bone. Inflammatory
cytokines, specifically, are crucial to skeletal homeostasis and any dysregulation can result …

Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

AG Renehan, M Tyson, M Egger, RF Heller, M Zwahlen - The lancet, 2008 - thelancet.com
Background Excess bodyweight, expressed as increased body-mass index (BMI), is
associated with the risk of some common adult cancers. We did a systematic review and …

A prospective study of obesity and cancer risk (Sweden)

A Wolk, G Gridley, M Svensson, O Nyrén… - Cancer causes & …, 2001 - Springer
Objective: We evaluated the relation between obesity and the risks for various forms of
cancer. Methods: In a population-based cohort of 28,129 hospital patients (8165 men …

Multiple myeloma: a review of the epidemiologic literature

DD Alexander, PJ Mink, HO Adami… - … journal of cancer, 2007 - Wiley Online Library
Multiple myeloma, a neoplasm of plasma cells, accounts for∼∼ 15% of
lymphatohematopoietic cancers (LHC) and 2% of all cancers in the US. Incidence rates …

Body mass index and risk of multiple myeloma: a meta-analysis of prospective studies

A Wallin, SC Larsson - European journal of cancer, 2011 - Elsevier
Excess body weight has been identified as a risk factor for various cancer types. Since the
publication of two meta-analyses indicating that body mass index (BMI) is positively …

Obesity and cancer risk among white and black United States veterans

C Samanic, G Gridley, WH Chow, J Lubin… - Cancer Causes & …, 2004 - Springer
Background: Obesity has been linked to excess risk for many cancers, but the evidence
remains tenuous for some types. Although the prevalence of obesity varies by race, few …

Obesity and the risk for a hematological malignancy: leukemia, lymphoma, or myeloma

MA Lichtman - The oncologist, 2010 - academic.oup.com
The aggregate of epidemiological studies indicates a significantly elevated risk for cancer in
people with a high body mass index (BMI); a “dose–response” effect exists with increasing …

Association of obesity and cancer risk in Canada

SY Pan, KC Johnson, AM Ugnat… - American journal of …, 2004 - academic.oup.com
The authors conducted a population-based, case-control study of 21,022 incident cases of
19 types of cancer and 5,039 controls aged 20–76 years during 1994–1997 to examine the …

Insulin and cancer: a tangled web

BP Leitner, S Siebel, ND Akingbesote… - Biochemical …, 2022 - portlandpress.com
For a century, since the pioneering work of Otto Warburg, the interwoven relationship
between metabolism and cancer has been appreciated. More recently, with obesity rates …

Multiple myeloma: challenges encountered and future options for better treatment

S Das, N Juliana, NAA Yazit, S Azmani… - International Journal of …, 2022 - mdpi.com
Multiple myeloma (MM) is a malignant hematological disease. The disease is characterized
by the clonal proliferation of malignant plasma cells in the bone marrow. MM accounts for …