Treatment of Benzodiazepine Dependence | New England Journal of Medicine Skip to main
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Exogenous melatonin has been investigated as treatment for a number of medical and
surgical diseases, demonstrating encouraging results. The aim of this review was to present …

Abstract gamma-Aminobutyric acid (GABA)-mediated inhibitory neurotransmission and the
gene products involved were discovered during the mid-twentieth century. Historically …

Rationale: Despite substantial public interest, few recommendations on the promotion of
good sleep health exist to educate health care providers and the general public on the …

BackgroundNumerous treatment guidelines recommend that long-term use of
benzodiazepines (BZD) should be avoided primarily due to development of tolerance and a …

Deteriorating sleep quality and physical or mental fatigue in older adults leads to decreased
quality of life and increased mortality rates. This study investigated the effects of the time …

Background. The global prevalence of stress is increasing. Stress adversely affects cognitive
ability, sleep quality, and overall psychological well‐being. Ashwagandha (Withania …

Sedatives are widely prescribed for anxiety or insomnia and include benzodiazepines,
selective benzodiazepine receptor subtype agonists (z-drugs), and barbiturates. These …

Importance The proportion of patients who develop long-term benzodiazepine use remains
controversial, as do the length of time before long-term use develops and the factors …

Objective The present study aims to systematically review all potentially inappropriate
medications for older persons included in prescribing criteria published in the last decade …