Elicitation: A biotechnological tool for enhanced production of secondary metabolites in hairy root cultures

M Halder, S Sarkar, S Jha - Engineering in life sciences, 2019 - Wiley Online Library
Elicitation is a possible aid to overcome various difficulties associated with the large‐scale
production of most commercially important bioactive secondary metabolites from wild and …

Hairy root cultures—a versatile tool with multiple applications

N Gutierrez-Valdes, ST Häkkinen… - Frontiers in plant …, 2020 - frontiersin.org
Hairy roots derived from the infection of a plant by Rhizobium rhizogenes (previously
referred to as Agrobacterium rhizogenes) bacteria, can be obtained from a wide variety of …

Plants and endophytes: equal partners in secondary metabolite production?

J Ludwig-Müller - Biotechnology letters, 2015 - Springer
Well known plant production systems should be re-evaluated due to findings that the
interesting metabolite might actually be produced by microbes intimately associated with the …

Production of plant secondary metabolites by using biotechnological tools

S Gonçalves, A Romano - Secondary metabolites-sources and …, 2018 - books.google.com
Plants are a remarkable source of high-value secondary metabolites with applications in
various domains. Plant cell and tissue culture techniques appear as environmentally friendly …

Biotic elicitors in adventitious and hairy root cultures: A review from 2010 to 2022

MA Alcalde, E Perez-Matas, A Escrich, RM Cusido… - Molecules, 2022 - mdpi.com
One of the aims of plant in vitro culture is to produce secondary plant metabolites using plant
cells and organ cultures, such as cell suspensions, adventitious, and hairy roots (among …

The regulatory mechanism of fungal elicitor-induced secondary metabolite biosynthesis in medical plants

X Zhai, M Jia, L Chen, C Zheng, K Rahman… - Critical reviews in …, 2017 - Taylor & Francis
A wide range of external stress stimuli trigger plant cells to undergo complex network of
reactions that ultimately lead to the synthesis and accumulation of secondary metabolites …

Genetically transformed roots: from plant disease to biotechnological resource

MI Georgiev, E Agostini, J Ludwig-Müller, J Xu - Trends in biotechnology, 2012 - cell.com
Hairy root syndrome is a disease that is induced by Agrobacterium rhizogenes infection and
characterized by a proliferation of excessively branching roots. However, in the past 30 …

Natural plant genetic engineer Agrobacterium rhizogenes: role of T-DNA in plant secondary metabolism

S Chandra - Biotechnology letters, 2012 - Springer
Agrobacterium rhizogenes is a natural plant genetic engineer. It is a gram-negative soil
bacterium that induces hairy root formation. Success has been obtained in exploring the …

Exudation: an expanding technique for continuous production and release of secondary metabolites from plant cell suspension and hairy root cultures

Z Cai, A Kastell, D Knorr, I Smetanska - Plant cell reports, 2012 - Springer
This review addresses methods of obtaining secondary metabolites from plant cell
suspension and hairy root cultures and their exudates, particularly the physiological …

Strategies to modulate specialized metabolism in Mediterranean crops: From molecular aspects to field

R Balestrini, C Brunetti, M Cammareri… - International Journal of …, 2021 - mdpi.com
Plant specialized metabolites (SMs) play an important role in the interaction with the
environment and are part of the plant defense response. These natural products are volatile …