Advances in droplet digital polymerase chain reaction on microfluidic chips
D Xu, W Zhang, H Li, N Li, JM Lin - Lab on a Chip, 2023 - pubs.rsc.org
The PCR technique has been known to the general public since the pandemic outbreak of
COVID-19. This technique has progressed through three stages: from simple PCR to real …
COVID-19. This technique has progressed through three stages: from simple PCR to real …
Biological biomarkers of oral cancer
A Radaic, P Kamarajan, A Cho, S Wang… - Periodontology …, 2023 - Wiley Online Library
The oral squamous cell carcinoma (OSCC) 5 year survival rate of 41% has marginally
improved in the last few years, with less than a 1% improvement per year from 2005 to 2017 …
improved in the last few years, with less than a 1% improvement per year from 2005 to 2017 …
Detection of occult recurrence using circulating tumor tissue modified viral HPV DNA among patients treated for HPV-driven oropharyngeal carcinoma
Purpose: Despite generally favorable outcomes, 15% to 25% of patients with human
papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma (OPSCC) will have …
papillomavirus (HPV)-driven oropharyngeal squamous cell carcinoma (OPSCC) will have …
Digital PCR for accurate quantification of pathogens: Principles, applications, challenges and future prospects
S Lei, S Chen, Q Zhong - International Journal of Biological …, 2021 - Elsevier
Pathogens pose a severe threat to food safety and human health. The traditional methods
for pathogen detection can't meet the growing diagnosis and control need. Digital PCR …
for pathogen detection can't meet the growing diagnosis and control need. Digital PCR …
Circulating HPV DNA as a marker for early detection of relapse in patients with cervical cancer
E Jeannot, A Latouche, C Bonneau… - Clinical Cancer …, 2021 - AACR
Purpose: Almost all cervical cancers are caused by human papillomavirus (HPV) and
patients with advanced stage are at high risk for relapse. Circulating HPV DNA (HPV ctDNA) …
patients with advanced stage are at high risk for relapse. Circulating HPV DNA (HPV ctDNA) …
[HTML][HTML] HPV and head and neck cancers: Towards early diagnosis and prevention
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide with an increasing trend of its incidence. Alcohol consumption, smoking, and viral …
worldwide with an increasing trend of its incidence. Alcohol consumption, smoking, and viral …
[HTML][HTML] Analytical validation of NavDx, a cfDNA-based fragmentomic profiling assay for HPV-driven cancers
A Gunning, S Kumar, CK Williams, BM Berger… - Diagnostics, 2023 - mdpi.com
The NavDx® blood test analyzes tumor tissue modified viral (TTMV)-HPV DNA to provide a
reliable means of detecting and monitoring HPV-driven cancers. The test has been clinically …
reliable means of detecting and monitoring HPV-driven cancers. The test has been clinically …
[HTML][HTML] Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma
Head and Neck cancers (HNC) are a heterogeneous group of upper aero-digestive tract
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …
[HTML][HTML] Current perspectives on recurrent HPV-mediated oropharyngeal cancer
In the recent years, the prevalence of HPV-positive oropharyngeal squamous cell carcinoma
(OPSCC) has increased significantly. Currently, nearly 80-90% of all oropharynx tumors are …
(OPSCC) has increased significantly. Currently, nearly 80-90% of all oropharynx tumors are …
[HTML][HTML] Liquid biopsy to detect minimal residual disease: methodology and impact
N Honoré, R Galot, C van Marcke, N Limaye… - Cancers, 2021 - mdpi.com
Simple Summary The field of liquid biopsy is rapidly evolving. Techniques that improve
accuracy are constantly being developed, and clinicians increasingly use liquid biopsy as a …
accuracy are constantly being developed, and clinicians increasingly use liquid biopsy as a …