Biological impact of environmental polycyclic aromatic hydrocarbons (ePAHs) as endocrine disruptors

Y Zhang, S Dong, H Wang, S Tao, R Kiyama - Environmental pollution, 2016 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are often detected in the environment and are
regarded as endocrine disruptors. We here designated mixtures of PAHs in the environment …

Air pollution: mechanisms of neuroinflammation and CNS disease

ML Block, L Calderón-Garcidueñas - Trends in neurosciences, 2009 - cell.com
Air pollution has been implicated as a chronic source of neuroinflammation and reactive
oxygen species (ROS) that produce neuropathology and central nervous system (CNS) …

Oxidative stress and air pollution exposure

M Lodovici, E Bigagli - Journal of toxicology, 2011 - Wiley Online Library
Air pollution is associated with increased cardiovascular and pulmonary morbidity and
mortality. The mechanisms of air pollution‐induced health effects involve oxidative stress …

Composition of air pollution particles and oxidative stress in cells, tissues, and living systems

AJ Ghio, MS Carraway, MC Madden - Journal of Toxicology and …, 2012 - Taylor & Francis
Epidemiological studies demonstrated an association between increased levels of ambient
air pollution particles and human morbidity and mortality. Production of oxidants, either …

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

ML Block, JS Hong - Progress in neurobiology, 2005 - Elsevier
Inflammation, a common denominator among the diverse list of neurodegenerative
diseases, has recently been implicated as a critical mechanism responsible for the …

Oxidative stress-induced DNA damage by particulate air pollution

L Risom, P Møller, S Loft - Mutation Research/Fundamental and Molecular …, 2005 - Elsevier
Exposure to ambient air particulate matter (PM) is associated with pulmonary and
cardiovascular diseases and cancer. The mechanisms of PM-induced health effects are …

The effect of fine and coarse particulate air pollution on mortality: a national analysis

A Zanobetti, J Schwartz - Environmental health perspectives, 2009 - ehp.niehs.nih.gov
Background Although many studies have examined the effects of air pollution on mortality,
data limitations have resulted in fewer studies of both particulate matter with an aerodynamic …

Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity

S Levesque, T Taetzsch, ME Lull… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Air pollution is linked to central nervous system disease, but the mechanisms
responsible are poorly understood. Objectives: Here, we sought to address the brain-region …

Outdoor ambient air pollution and neurodegenerative diseases: the neuroinflammation hypothesis

RL Jayaraj, EA Rodriguez, Y Wang… - Current environmental …, 2017 - Springer
Abstract Purpose of Review Accumulating research indicates that ambient outdoor air
pollution impacts the brain and may affect neurodegenerative diseases, yet the potential …

Inflammation as a causative factor in the aetiology of Parkinson's disease

PS Whitton - British journal of pharmacology, 2007 - Wiley Online Library
Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting mainly the
elderly, although a small proportion of PD patients develop the illness at a much younger …