Purpose The objectives of this study were to explore the factors influencing urinary 8-
hydroxy-2′-deoxyguanosine (8-OHdG) levels in diesel engine exhaust emission inspectors …

The capacity of particulate matter (PM) to enhance and stimulate the expression of pro-
inflammatory mediators has been previously demonstrated in non-antigen-presenting cells …

Broadly, the health-relevant aerosols to be considered can be classified into those derived
from the activities of man (eg, combustion of fuels) and those that occur in natural …

The mechanism for how inhaled particles cause or exacerbate human diseases is not
known. It is clear, however, that some particles are more bioactive than others. One possible …

Often, the effects observed in epidemiological studies cannot be attributed to the specific
indicators addressed, but to a mixture of pollutants. Fine PM (including black smoke) and …

A new procedure for isolating and estimating ingested carbonaceous diesel exhaust
particles (DEP) or carbon black (CB) particles by lung epithelial cells and macrophages is …

Accumulating evidence suggests a deleterious role for urban air pollution in central nervous
system (CNS) diseases and neurodevelopmental disorders. Microglia, the resident innate …

Exposure to diesel exhaust particles (DEP) was shown to increase the susceptibility of the
lung to bacterial infection in rats. In this study, the effects of DEP on alveolar macrophage …

Diesel exhaust particles (DEP) have been shown to alter pulmonary immune responses to
bacterial infection. Exposure of rats to 100 mg/m3 DEP for 4 h was found to aggravate …

Background Diesel exhaust is associated with cardiovascular and respiratory mortality and
morbidity. Acute exposure leads to increased IL-8 expression and airway neutrophilia …