Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …

Integration of data across spatial, temporal, and functional scales is a primary focus of
biomedical engineering efforts. The advent of powerful computing platforms, coupled with …

Two major mechanisms are involved in the formation of blood vasculature: vasculogenesis
and angiogenesis. The former term describes the formation of a capillary-like network from …

We present comprehensive mathematical modeling of radiopharmaceutical spatiotemporal
distributions within vascularized solid tumors. The novelty of the presented model is at …

Tumor associated angiogenesis is the development of new blood vessels in response to
proteins secreted by tumor cells. These new blood vessels allow tumors to continue to grow …

We demonstrate ensemble three-dimensional cell cultures and quantitative analysis of
angiogenic growth from uniform endothelial monolayers. Our approach combines two key …

Cancerous tumours have the ability to recruit new blood vessels through a process called
angiogenesis. By stimulating vascular growth, tumours get connected to the circulatory …

Angiogenesis is the formation of new blood vessels from pre-existing ones in response to
chemical signals secreted by, for example, a wound or a tumour. In this paper, we propose a …

Angiogenesis, the formation of new bloods vessels from the existing vasculature, is a
process that is essential during development and regeneration of tissues, and that plays a …

Bone regeneration has long been a major focus for tissue engineers and the importance of
vascularization to the bone regeneration process has been well documented. Over the past …