Psychomotor function and psychoactive drugs
I Hindmarch - Methods in clinical pharmacology—central nervous …, 1981 - Springer
Busch, Klapproth, Lucker & Schmitz (1979), concentration; Hindmarch & Parrott (1978), a
concept identification task; Jones, Lewis & Spriggs (1978), a group vigilance task; Bond & …
concept identification task; Jones, Lewis & Spriggs (1978), a group vigilance task; Bond & …
Residual effects of hypnotics: epidemiology and clinical implications
A Vermeeren - CNS drugs, 2004 - Springer
The risk of 'hangover'effects, eg residual daytime sleepiness and impairment of psychomotor
and cognitive functioning the day after bedtime administration, is one of the main problems …
and cognitive functioning the day after bedtime administration, is one of the main problems …
Sedative-hypnotics and human performance
LC Johnson, DA Chernik - Psychopharmacology, 1982 - Springer
In 52 studies, performance data were obtained the next day following bedtime ingestion of a
sedative-hypnotic or a placebo. Only eight of these studies used insomniac patients. Most …
sedative-hypnotic or a placebo. Only eight of these studies used insomniac patients. Most …
Benzodiazepines: clinical pharmacology and therapeutic use
C Bellantuono, V Reggi, G Tognoni, S Garattini - Drugs, 1980 - Springer
Benzodiazepines: Clinical Pharmacology and Therapeutic Use deniable (see also table IV)
as it regularly includes a substantial part of the population. Differences in utilisation of …
as it regularly includes a substantial part of the population. Differences in utilisation of …
Kinetics and clinical effects of flurazepam in young and elderly noninsomniacs
DJ Greenblatt, M Divoll, JS Harmatz… - Clinical …, 1981 - Wiley Online Library
Twenty‐six healthy subjects from 19 to 85 yr old took single 15‐mg doses of flurazepam
(FLZ). Concentrations of desalkylflurazepam (DAFLZ), its principal metabolite, were …
(FLZ). Concentrations of desalkylflurazepam (DAFLZ), its principal metabolite, were …
Drugs, alcohol and driving
T Seppala, M Linnoila, MJ Mattila - Drugs, 1979 - Springer
Driving a car is a complex psychomotor and perceptual task which is subject to impairment
by many factors. Several workers have studied the potential effects of drugs and alcohol in …
by many factors. Several workers have studied the potential effects of drugs and alcohol in …
Visual motor co‐ordination and dynamic visual acuity.
RG Borland, AN Nicholson - British journal of clinical …, 1984 - Wiley Online Library
Data on the effect of an antihistamine (triprolidine 10 mg) on visuo‐motor coordination and
dynamic visual acuity were used to establish interactions between these skills. Analysis of …
dynamic visual acuity were used to establish interactions between these skills. Analysis of …
Clinical pharmacokinetics of hypnotics
DD Breimer - Clinical pharmacokinetics, 1977 - Springer
The intermittent type of drug action which is desired in hypnotic treatment is fundamentally
different from those types of drug treatment where a constant effect is required. Thus, in …
different from those types of drug treatment where a constant effect is required. Thus, in …
Pharmacokinetics, pharmacodynamics and the pharmacokinetic/pharmacodynamic relationship of zolpidem in healthy subjects
SL De Haas, RC Schoemaker… - Journal of …, 2010 - journals.sagepub.com
Zolpidem is one of the most frequently prescribed hypnotics, as it is a very short-acting
compound with relatively few side effects. Zolpidem's short duration of action is partly related …
compound with relatively few side effects. Zolpidem's short duration of action is partly related …
Performance studies with antihistamines.
CH Clarke, AN Nicholson - British journal of clinical …, 1978 - Wiley Online Library
1 Effect of four antihistamines, chlorpheniramine (4 mg), clemastine (1 mg), promethazine
(10 mg) and terfenadine (60 mg), on visuo‐motor coordination and on subjective …
(10 mg) and terfenadine (60 mg), on visuo‐motor coordination and on subjective …