Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Testing at scale during the COVID-19 pandemic

TR Mercer, M Salit - Nature Reviews Genetics, 2021 - nature.com
Assembly and publication of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome in January 2020 enabled the immediate development of tests to detect the …

[HTML][HTML] Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients

TS Rodrigues, KSG de Sá, AY Ishimoto… - Journal of Experimental …, 2021 - rupress.org
Severe cases of COVID-19 are characterized by a strong inflammatory process that may
ultimately lead to organ failure and patient death. The NLRP3 inflammasome is a molecular …

COVID-19 diagnosis—A review of current methods

M Yüce, E Filiztekin, KG Özkaya - Biosensors and Bioelectronics, 2021 - Elsevier
A fast and accurate self-testing tool for COVID-19 diagnosis has become a prerequisite to
comprehend the exact number of cases worldwide and to take medical and governmental …

First confirmed detection of SARS-CoV-2 in untreated wastewater in Australia: a proof of concept for the wastewater surveillance of COVID-19 in the community

W Ahmed, N Angel, J Edson, K Bibby, A Bivins… - Science of the Total …, 2020 - Elsevier
Abstract Infection with SARS-CoV-2, the etiologic agent of the ongoing COVID-19 pandemic,
is accompanied by the shedding of the virus in stool. Therefore, the quantification of SARS …

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

FP Veras, MC Pontelli, CM Silva… - Journal of Experimental …, 2020 - rupress.org
Severe COVID-19 patients develop acute respiratory distress syndrome that may progress to
cytokine storm syndrome, organ dysfunction, and death. Considering that neutrophil …

[HTML][HTML] SARS-CoV-2 in wastewater: State of the knowledge and research needs

M Kitajima, W Ahmed, K Bibby, A Carducci… - Science of The Total …, 2020 - Elsevier
The ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a Public Health …

[HTML][HTML] Analytical sensitivity and efficiency comparisons of SARS-CoV-2 RT–qPCR primer–probe sets

CBF Vogels, AF Brito, AL Wyllie, JR Fauver, IM Ott… - Nature …, 2020 - nature.com
The recent spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
exemplifies the critical need for accurate and rapid diagnostic assays to prompt clinical and …

Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate

A Addetia, KHD Crawford, A Dingens… - Journal of clinical …, 2020 - Am Soc Microbiol
The development of vaccines against SARS-CoV-2 would be greatly facilitated by the
identification of immunological correlates of protection in humans. However, to date, studies …

[HTML][HTML] Molecular diagnostic technologies for COVID-19: Limitations and challenges

A Afzal - Journal of advanced research, 2020 - Elsevier
Background To curb the spread of the COVID-19 (coronavirus disease 2019) pandemic, the
world needs diagnostic systems capable of rapid detection and quantification of the novel …