A conceptual framework of frailty: a review

WM Bortz - The Journals of Gerontology Series A: Biological …, 2002 - academic.oup.com
This article presents an overview of the increasingly common condition of frailty, which by
and large lacks clarity of definition. A variety of sources provide this statement regarding …

Accumulation of senescent cells in mitotic tissue of aging primates

JC Jeyapalan, M Ferreira, JM Sedivy… - Mechanisms of ageing and …, 2007 - Elsevier
Cellular senescence, a stress induced growth arrest of somatic cells, was first documented
in cell cultures over 40 years ago, however its physiological significance has only recently …

Is osteoporosis a predictor for future sarcopenia or vice versa? Four-year observations between the second and third ROAD study surveys

N Yoshimura, S Muraki, H Oka, T Iidaka… - Osteoporosis …, 2017 - Springer
In a 4-year follow-up study that enrolled 1099 subjects aged≥ 60 years, sarcopenia
prevalence was estimated at 8.2%. Moreover, the presence of osteoporosis was significantly …

Chronic pain management in the elderly

J Schwan, J Sclafani, VL Tawfik - Anesthesiology …, 2019 - anesthesiology.theclinics.com
Chronic pain is one of the most common health conditions among older adults (> 65 years)
and is associated with significant disability. Chronic pain in the older adult reduces mobility …

Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial

MH Emmelot-Vonk, HJJ Verhaar, HRN Pour, A Aleman… - Jama, 2008 - jamanetwork.com
Context Serum testosterone levels decline significantly with aging. Testosterone
supplementation to older men might beneficially affect the aging processes. ObjectiveTo …

[HTML][HTML] Strong or weak handgrip? Normative reference values for the German population across the life course stratified by sex, age, and body height

N Steiber - PloS one, 2016 - journals.plos.org
Handgrip strength is an important biomarker of healthy ageing and a powerful predictor of
future morbidity and mortality both in younger and older populations. Therefore, the …

Muscle wasting in cancer cachexia: clinical implications, diagnosis, and emerging treatment strategies

S Dodson, VE Baracos, A Jatoi, WJ Evans… - Annual review of …, 2011 - annualreviews.org
Cancer cachexia is a complex metabolic condition characterized by loss of skeletal muscle.
Common clinical manifestations include muscle wasting, anemia, reduced caloric intake …

Prevalence and prognostic effect of sarcopenia in breast cancer survivors: the HEAL Study

A Villaseñor, R Ballard-Barbash, K Baumgartner… - Journal of Cancer …, 2012 - Springer
Purpose This study aimed to determine the prevalence of sarcopenia and examine whether
sarcopenia was associated with overall and breast-cancer-specific mortality in a cohort of …

Effects of exercise on muscle mass, strength, and physical performance in older adults with sarcopenia: A systematic review and meta-analysis according to the …

A Escriche-Escuder, IJ Fuentes-Abolafio… - Experimental …, 2021 - Elsevier
Abstract Background In 2018, the European Working Group on Sarcopenia in Older People
(EWGSOP) updated the definition and the diagnosis criteria of sarcopenia. Previous …

[HTML][HTML] An update on protein, leucine, omega-3 fatty acids, and vitamin D in the prevention and treatment of sarcopenia and functional decline

AJ Tessier, S Chevalier - Nutrients, 2018 - mdpi.com
Aging is associated with sarcopenia and functional decline, leading to frailty and disability.
As a modifiable risk factor, nutrition may represent a target for preventing or postponing the …