The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

Spinal cord injury (SCI) is a disabling condition that disrupts motor, sensory, and autonomic
functions. Despite extensive research in the last decades, SCI continues to be a global …

Preclinical and clinical studies with various stem cells, their secretomes, and extracellular
vesicles (EVs) indicate their use as a promising strategy for the treatment of various …

Sex differences in motivation for food rewards, gambling, and drugs of abuse are modulated
by multiple factors, including sensory stimuli, gonadal hormones, and cognitive bias. Cues …

Chondroitin sulfate (CS) is the most abundant and widely distributed glycosaminoglycan
(GAG) in the human body. As a component of proteoglycans (PGs) it has numerous roles in …

Background. The extracellular matrix of the PNS/CNS is unusual in that it is dominated by
glycosaminoglycans, especially hyaluronan, whose space filling and hydrating properties …

Chondroitin sulfate (CS) is a major component of the extracellular matrix found to be
abnormally accumulated in several types of cancer tissues. Previous studies have indicated …

Individual treatment outcomes to antidepressants varies widely, yet the determinants to this
difference remain elusive. MicroRNA (miRNA) gene expression regulation in major …

Ischemic stroke is a leading cause of long-term disability and a severe social and economic
burden. After ischemic stroke, the central nervous system (CNS) microenvironment at the …

Protein glycosylation, which involves the attachment of carbohydrates to proteins, is one of
the most abundant protein co-translational and post-translational modifications. Advances in …